Weight | 282.295 g/mol |
---|---|
Formula | C17H14O4 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 3 |
Rotatable Bonds | 2 |
DMXAA (117570-53-3)
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- Sigma-Aldrich - DMXAA186.50 - 642.00 USD
- Fisher Scientific - Search for DMXAA
- TCI - Search for DMXAA
- Structure-Function Analysis of STING Activation by c[G(2,5)pA(3,5)p] and Targeting by Antiviral DMXAA (Cell, 2013)
- Antivascular therapy of cancer: DMXAA (Lancet Oncology, 2003)
- Clinical aspects of a phase I trial of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent (British Journal of Cancer, 2003)
- The chemotherapeutic agent DMXAA potently and specifically activates the TBK1IRF-3 signaling axis (Journal of Experimental Medicine, 2007)
- Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs (British Journal of Cancer, 1998)
- 5,6-Dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent: phase I clinical and pharmacokinetic study (British Journal of Cancer, 2003)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=C(C2=C(C=C1)C(=O)C3=C(O2)C(=CC=C3)CC(=O)O)C
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- Pubchem - DMXAA
- Wikipedia - vadimezan
Vadimezan (also known as or ASA404 and DMXAA) is a tumor-vascular disrupting agent (tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression.
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