Dulcin (150-69-6)

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  500 mg
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  1 g
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  500 mg
  $143.00

  1 g
  $201.00

Most-cited Publications

• The genetics of tasting in mice. VI. Saccharin, acesulfame, dulcin and sucrose. (Genetics Research, 1989)
• Dulcin and Saccharin Taste in Squirrel Monkeys, Rats, and Men (Science, 1965)
• Studies on food additives. X. The metabolism of p-ethoxyphenylurea in the rabbit. (Chemical & Pharmaceutical Bulletin, 1966)
• Trennung, Nachweis und Bestimmung der knstlichen Sstoffe Cyclamat, Dulcin und Saccharin mittels Gas-Chromatographie (Fresenius Journal of Analytical Chemistry, 1971)
• Dnnschichtchromatographische Trennung und Identifizierung von Saccharin, Cyclamat und Dulcin (European Food Research and Technology, 1964)
• DERIVATIVES OF DULCIN (Journal of the American Chemical Society, 1931)

Areas of Application

Safety

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Trends

Alternate Names

• phenetolcarbamide
• p-ethoxyphenylurea
• SMILES
  CCOC1=CC=C(C=C1)NC(=O)N
• InChIKey
  GGLIEWRLXDLBBF-UHFFFAOYSA-N

External Links

• Pubchem - Dulcin
• Wikipedia - dulcin
  Dulcin is an artificial sweetener about 250 times sweeter than sugar, discovered in 1883 by the Polish chemist Jzef (Joseph) Berlinerblau (27 August 1859 1935). It was first mass-produced about seven years later. Although it was discovered only five years after saccharin, it never enjoyed the latter compounds market success.

Synthesis

Isocyanic acid  +  4-ETHOXYANILINE (Thiourea)

1-(4-hydroxyphenyl)urea  +  Chloroethane (Williamson ether)

Carbamyl chloride  +  4-ETHOXYANILINE (Schotten-Baumann amide from acid)

Reactant  +  Ureidoradical (Chan-Lam coupling reaction)

Reactant  +  ETHYL HYDROPEROXIDE (Dakin oxidation)

Synthesis of Dulcin ›

Similar Compounds

4-Methoxyphenylurea (1566-42-3)

3 alternate names

3 suppliers

1,3-bis(4-methoxyphenyl)urea (1227-44-7)

3 alternate names

3 suppliers

N-(4-Methoxyphenyl)formamide (5470-34-8)

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1-(3-methoxyphenyl)urea (139-77-5)

3 alternate names

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880-29-5 (880-29-5)

3 alternate names

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65536-40-5 (65536-40-5)

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6622-73-7 (6622-73-7)

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50375-15-0 (50375-15-0)

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N-(4-isopropoxyphenyl)acetamide (7146-61-4)

3 alternate names

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Etocarlide (1234-30-6)

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N-(4-Butoxyphenyl)acetamide (23563-26-0)

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N-(4-Methoxyphenyl)acetamide (51-66-1)

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2-Iodo-p-acetophenetidide (17641-13-3)

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2-chloro-N-(4-ethoxyphenyl)acetamide (2153-08-4)

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4-Methoxy-N-methylaniline (5961-59-1)

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3-HYDROXYPHENYLUREA (701-82-6)

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1-(4-Methoxyphenyl)thiourea (2293-07-4)

3 alternate names

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N-[4-(octyloxy)phenyl]acetamide (55792-63-7)

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(4-acetamidophenoxy)acetic acid (39149-13-8)

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2-cyano-N-(4-ethoxyphenyl)acetamide (51838-07-4)

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4-hydroxyphenylformamide (1693-39-6)

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356539-16-7 (356539-16-7)

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2-CHLORO-N-(4-ISOPROPOXYPHENYL)ACETAMIDE (100129-54-2)

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1-(2-Methoxyphenyl)urea (135-92-2)

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Methyl N-(4-methoxyphenyl)carbamate (14803-72-6)

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4-Methoxy-N,N-dimethylaniline (701-56-4)

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4-ETHOXYANILINE (156-43-4)

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8 safety hazards

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N-allyl-4-methoxyaniline (71954-46-6)

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2-bromo-N-(4-methoxyphenyl)acetamide (29182-87-4)

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2-Chloro-N-(4-methoxyphenyl)acetamide (22303-36-2)

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4-(allyloxy)aniline (1688-69-3)

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4-(4-Methoxyphenyl)-3-thiosemicarbazide (40207-03-2)

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1737-06-0 (1737-06-0)

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[4-(propionylamino)phenoxy]acetic acid (890982-09-9)

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2-(4-ethoxyanilino)acetohydrazide (100133-39-9)

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4-Propoxyaniline (4469-80-1)

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N-(4-Ethoxyphenyl)-3-oxobutanamide (122-82-7)

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n-methyl-4-(trifluoromethoxy)aniline (41419-59-4)

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N-(2-Amino-4-ethoxyphenyl)acetamide (67169-91-9)

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4-[3-(4-aminophenoxy)propoxy]aniline (52980-20-8)

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2-Cyano-N-(4-methoxyphenyl)acetamide (5382-38-7)

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Ethanol, 2-(4-aminophenoxy)-, hydrochloride (61886-41-7)

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3-[(4-ethoxyphenyl)amino]-3-oxopropanoic acid (4270-38-6)

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4-(2-phenoxyethoxy)aniline (35965-96-9)

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3 suppliers

4-Isobutoxyaniline (5198-04-9)

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67202-81-7 (67202-81-7)

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1-Phenylurea (64-10-8)

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3 suppliers

4-Isopropoxyaniline (7664-66-6)

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3-chloro-n-(4-methoxyphenyl)propanamide (19313-87-2)

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4-[(4-ethoxyphenyl)amino]-4-oxobutanoic acid (59256-45-0)

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1-(4-methoxyphenyl)imidazolidin-2-one (14599-72-5)

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N-benzyl-4-ethoxyaniline (72753-31-2)

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4-Butoxyaniline (4344-55-2)

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N-(3-Methoxyphenyl)acetamide (588-16-9)

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(4-amino-phenyl)-urea (21492-80-8)

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1-(4-ethoxyphenyl)piperazine (46415-29-6)

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{4-[(2-methyl-2-propen-1-yl)oxy]phenyl}amine hydrochloride (1049787-10-1)

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3-ACETAMIDOPHENYL ACETATE (6317-89-1)

3 alternate names

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N-(3,4-Dimethoxyphenyl)acetamide (881-70-9)

3 alternate names

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4-Ethoxyphenyl isothiocyanate (3460-49-9)

3 alternate names

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4-aminophenyl acetate (13871-68-6)

3 alternate names

3 suppliers

N,N'-bis(4-methoxyphenyl)propanediamide (15589-58-9)

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4-(2-methoxyethoxy)aniline hydrochloride (10141-52-3)

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3 suppliers

4-(2-methoxyethoxy)aniline (33311-29-4)

3 alternate names

3 suppliers

4-Pentyloxyaniline (39905-50-5)

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3 suppliers

161290-85-3 (161290-85-3)

3 alternate names

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N-(3-hydroxyphenyl)formamide (24891-35-8)

3 alternate names

3 suppliers

4-Ethoxyphenyl isocyanate (32459-62-4)

3 alternate names

3 suppliers

3-acetamidophenoxyacetic acid (6339-04-4)

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79476-73-6 (79476-73-6)

3 alternate names

3 suppliers

N-(2-Amino-4-methoxyphenyl)acetamide (5472-37-7)

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4-(2-ethoxyethoxy)aniline (65999-71-5)

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4-(2-ETHOXYETHOXY)ANILINE HYDROCHLORIDE (1049750-45-9)

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N-(3-Amino-4-methoxyphenyl)acetamide (6375-47-9)

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5437-98-9 (5437-98-9)

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6375-47-9 (6375-47-9)

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65069-53-6 (65069-53-6)

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3-[(4-methoxyphenyl)amino]-3-oxopropanoic acid (61916-60-7)

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4-(Methylamino)phenol (150-75-4)

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4-Hexyloxyaniline (39905-57-2)

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2-hydrazino-N-(4-methoxyphenyl)-2-oxoacetamide (20580-47-6)

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p-Decyloxyaniline (39905-47-0)

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4-Heptyloxyaniline (39905-44-7)

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(4-SEC-BUTOXYPHENYL)AMINE HYDROCHLORIDE (1087751-49-2)

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p-Nonyloxyaniline (50262-67-4)

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4-Octyloxyaniline (39905-45-8)

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p-Hexadecyloxyaniline (7502-06-9)

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2-(4-aminophenoxy)acetic acid (2298-36-4)

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13067-19-1 (13067-19-1)

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p-Anisidine (104-94-9, 29191-52-4)

3 alternate names

3 safety hazards

3 suppliers

Parapropamol (1693-37-4)

3 alternate names

3 suppliers

4-(2-(2-Methoxyethoxy)ethoxy)aniline (65673-48-5)

3 alternate names

3 suppliers

m-Phenetidine (621-33-0)

3 alternate names

3 suppliers

N-(3,5-dimethoxyphenyl)acetamide (79257-61-7)

3 alternate names

3 suppliers

N-(4-bromophenyl)-2-phenoxyacetamide (18861-19-3)

3 alternate names

3 suppliers

N,N-Dimethyl-m-anisidine (15799-79-8)

3 alternate names

3 suppliers

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Dulcin

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