| Weight | 331.84 g/mol |
|---|---|
| Formula | C16H26ClNO4 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 9 |
Esmolol hydrochloride (81161-17-3)
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- ESMOLOL HYDROCHLORIDE FOR MANAGEMENT OF THE CARDIOVASCULAR STRESS RESPONSES TO LARYNGOSCOPY AND TRACHEAL INTUBATION (BJA: British Journal of Anaesthesia, 1992)
- Esmolol hydrochloride: an ultrashort-acting, beta-adrenergic blocking agent. (Clinical pharmacy, 1986)
- Esmolol hydrochloride, sodium nitroprusside, and isoflurane differ in their ability to alter peripheral sympathetic responses. (Anesthesia & Analgesia, 1993)
- High-Performance Liquid Chromatographic Method for the Determination of Esmolol Hydrochloride (Journal of Pharmaceutical Sciences, 1984)
- Stability of esmolol hydrochloride in the presence of aminophylline, bretylium tosylate, heparin sodium, and procainamide hydrochloride (American Journal of Health-system Pharmacy, 1990)
- Compatibility of esmolol hydrochloride with morphine sulfate and fentanyl citrate during simulated Y-site administration (American Journal of Health-system Pharmacy, 1988)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)NCC(COC1=CC=C(C=C1)CCC(=O)OC)O.Cl
-
InChIKeyGEKNCWBANDDJJL-UHFFFAOYSA-N
- Pubchem - Esmolol hydrochloride
- Wikipedia - esmolol hydrochloride
Esmolol (trade name Brevibloc) is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages. It is a class II antiarrhythmic. Esmolol decreases the force and rate of heart contractions by blocking beta-adrenergic receptors of the sympathetic nervous system, which are found in the heart and other organs of the body.
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Synthesis
ISOPROPYLAMINE
+
Reactant
(Alkylation of primary amines)
Methyl 3-(4-hydroxyphenyl)propionate
+
Reactant
(Williamson ether)
Reactant
+
CID 5475562
(Chan-Lam coupling reaction)
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Esmolol hydrochloride
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