Weight | 157.213 g/mol |
---|---|
Formula | C8H15NO2 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 0 |
Rotatable Bonds | 2 |
Ethyl nipecotate (71962-74-8, 5006-62-2)
nipecotic acid ethyl ester, (R)-isomer · nipecotic acid ethyl ester
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- (R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors. (Journal of Pharmacology and Experimental Therapeutics, 1987)
- Differential effects of ethyl (R,S)-nipecotate on the behaviors of highly and minimally aggressive female golden hamsters (Psychopharmacology, 1986)
- Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by Ethyl Nipecotate-derived New Chiral Ligand (Heterocycles, 1999)
- Determination of chiral purity of ethyl nipecotate using a Chiralcel-OG column (Journal of Chromatography A, 1995)
- Synthesis of (R) and (S) 14C-labelled ethyl nipecotate, for preparation of GABA uptake ligands (Journal of Labelled Compounds and Radiopharmaceuticals, 1997)
- Activity of N-ethyl-nor-arecaidine Propargyl Ester and (R)-nipecotic Acid Ethyl Ester at Pre- and Postsynaptic Muscarinic Receptor Subtypes (1991)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - nipecotic acid ethyl ester, (R)-isomer
- nipecotic acid ethyl ester
-
SMILESCCOC(=O)C1CCCNC1
-
InChIKeyXIWBSOUNZWSFKU-UHFFFAOYSA-N
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Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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