Weight | 296.41 g/mol |
---|---|
Formula | C20H24O2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 0 |
Aromatic Rings | 0 |
Rotatable Bonds | 0 |
EXEMESTANE (107868-30-4)
Score:
#451 in Biochemistry
,
#1724 in Chemistry
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- A Randomized Trial of Exemestane after Two to Three Years of Tamoxifen Therapy in Postmenopausal Women with Primary Breast Cancer (The New England Journal of Medicine, 2004)
- Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup Exemestane Study): a randomised controlled trial (The Lancet, 2007)
- Exemestane for Breast-Cancer Prevention in Postmenopausal Women (The New England Journal of Medicine, 2011)
- Exemestane Is Superior to Megestrol Acetate After Tamoxifen Failure in Postmenopausal Women With Advanced Breast Cancer: Results of a Phase III Randomized Double-Blind Trial (Journal of Clinical Oncology, 2000)
- Double-Blind, Randomized Placebo Controlled Trial of Fulvestrant Compared With Exemestane After Prior Nonsteroidal Aromatase Inhibitor Therapy in Postmenopausal Women With Hormone ReceptorPositive, Advanced Breast Cancer: Results From EFECT (Journal of Clinical Oncology, 2008)
- Skeletal effects of exemestane on bone-mineral density, bone biomarkers, and fracture incidence in postmenopausal women with early breast cancer participating in the Intergroup Exemestane Study (IES): a randomised controlled study (Lancet Oncology, 2007)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC12CCC3C(C1CCC2=O)CC(=C)C4=CC(=O)C=CC34C
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InChIKeyBFYIZQONLCFLEV-UHFFFAOYSA-N
- Pubchem - EXEMESTANE
- Wikipedia - exemestane
Exemestane, sold under the brand name Aromasin among others, is a medication used to treat breast cancer. It is a member of the class of antiestrogens known as aromatase inhibitors. Some breast cancers require estrogen to grow.
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