| Weight | 378.435 g/mol |
|---|---|
| Formula | C24H18N4O |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 5 |
| Rotatable Bonds | 2 |
Go 6976 (136194-77-9)
Go-6976 · Go6976 · Goe 6976
Score:
#1261 in Neuroscience
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#2955 in Biochemistry
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#5412 in Biology
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#7235 in Chemistry
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- Selective inhibition of protein kinase C isozymes by the indolocarbazole G 6976. (Journal of Biological Chemistry, 1993)
- The Protein Kinase C Inhibitor G6976 Is a Potent Inhibitor of DNA Damage-induced S and G2 Cell Cycle Checkpoints (Cancer Research, 2003)
- G 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro. (Proceedings of the National Academy of Sciences of the United States of America, 1993)
- Protein Kinase C / Inhibitor Go6976 Promotes Formation of Cell Junctions and Inhibits Invasion of Urinary Bladder Carcinoma Cells (Cancer Research, 2004)
- G6976 is a potent inhibitor of the JAK 2 and FLT3 tyrosine kinases with significant activity in primary acute myeloid leukaemia cells (British Journal of Haematology, 2006)
- Atypical Isoforms of PKC and Insulin Secretion from Pancreatic -Cells: Evidence Using G 6976 and Ro 31-8220 as PKC Inhibitors (Biochemical and Biophysical Research Communications, 1996)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Go-6976
- Go6976
- Goe 6976
-
SMILESCN1C2=CC=CC=C2C3=C4C(=C5C6=CC=CC=C6N(C5=C31)CCC#N)CNC4=O
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InChIKeyVWVYILCFSYNJHF-UHFFFAOYSA-N
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