| Weight | 212.252 g/mol |
|---|---|
| Formula | C13H12N2O |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 1 |
HARMINE (442-51-3)
Telepathine · Banisterine · Leucoharmine
Score:
#788 in Neuroscience
,
#1471 in Biochemistry
,
#3466 in Biology
,
#4331 in Chemistry
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- The Small Molecule Harmine Is an Antidiabetic Cell-Type-Specific Regulator of PPAR Expression (Cell Metabolism, 2007)
- Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation (FEBS Journal, 2009)
- Antitumor agents 201.1 Cytotoxicity of harmine and -carboline analogs (Bioorganic & Medicinal Chemistry Letters, 1999)
- HPLC method for the analysis of harmol, harmalol, harmine and harmaline in the seeds of Peganum harmala L. (Journal of Pharmaceutical and Biomedical Analysis, 2003)
- Specific inhibition of cyclin-dependent kinases and cell proliferation by harmine (Biochemical and Biophysical Research Communications, 2004)
- DNA binding properties of 9-substituted harmine derivatives. (Biochemical and Biophysical Research Communications, 2005)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Telepathine
- Banisterine
- Leucoharmine
- Yageine
-
SMILESCC1=NC=CC2=C1NC3=C2C=CC(=C3)OC
-
InChIKeyBXNJHAXVSOCGBA-UHFFFAOYSA-N
- Pubchem - HARMINE
- Wikipedia - harmine
Harmine, also known as telepathine, is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds. It occurs in a number of different plants, most notably the Middle Eastern plant harmal or Syrian rue (Peganum harmala) and the South American vine Banisteriopsis caapi (also known as "yage" or "ayahuasca"). Harmine reversibly inhibits monoamine oxidase A (MAO-A), an enzyme which breaks down monoamines, making it a RIMA.
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HARMINE
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