| Weight | 261.365 g/mol |
|---|---|
| Formula | C16H23NO2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 5 |
HEXYLCAINE (532-77-4)
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- ELECTROCARDIOGRAPHIC STUDIES DURING ENDOTRACHEAL INTUBATION. V. EFFECTS DURING GENERAL ANESTHESIA AND HEXYLCAINE HYDROCHLORIDE TOPICAL SPRAY (Anesthesiology, 1953)
- Hexylcaine (cyclaine); usefulness in regional and topical anesthesia; preliminary report. (Anesthesiology, 1952)
- Hexylcaine hydrochloride: A preliminary report of its clinical use in comparison with procaine (American Journal of Surgery, 1949)
- Clinical use of cyclaine (hexylcaine hydrochloride) for spinal and regional nerve block: report of 2000 cases. (Anesthesiology, 1952)
- A COMPARATIVE STUDY OF THE ACTIVITY AND TOXICITY OF HEXYLCAINE (1-CYCLOHEXYLAMINO-2-PROPYLBENZOATE); A NEW LOCAL ANESTHETIC AGENT (Journal of Pharmacology and Experimental Therapeutics, 1948)
- Clinical experience with Hexylcaine hydrochloride (cyclaine) (Canadian Journal of Anaesthesia-journal Canadien D Anesthesie, 1954)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(CNC1CCCCC1)OC(=O)C2=CC=CC=C2
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InChIKeyDKLKMKYDWHYZTD-UHFFFAOYSA-N
- Pubchem - HEXYLCAINE
- Wikipedia - hexylcaine
Hexylcaine hydrochloride, also called cyclaine (Merck) or osmocaine, is a short-acting local anesthetic. It acts by inhibiting sodium channel conduction. Overdose can lead to headache, tinnitus, numbness and tingling around the mouth and tongue, convulsions, inability to breathe, and decreased heart function.
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Synthesis
CYCLOHEXYLAMINE
+
Reactant
(Alkylation of primary amines)
Reactant
+
Cyclohexylamino radical
(Chan-Lam coupling reaction)
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