| Weight | 196.641 g/mol |
|---|---|
| Formula | C8H9ClN4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 1 |
HYDRALAZINE HYDROCHLORIDE (304-20-1)
Hydralazine · Apresoline · Hydrazinophthalazine
Score:
#324 in Biochemistry
,
#1198 in Biology
,
#1373 in Chemistry
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- A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure (The New England Journal of Medicine, 1991)
- Combination of isosorbide dinitrate and hydralazine in blacks with heart failure. (The New England Journal of Medicine, 2004)
- Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drug. (Journal of Clinical Investigation, 1996)
- Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity. (Journal of Immunology, 1988)
- Hydralazine-induced systemic lupus erythematosus: influence of HLA-DR and sex on susceptibility. (The Lancet, 1980)
- Late toxicity to hydralazine resembling systemic lupus erythematosus or rheumatoid arthritis. (The American Journal of Medicine, 1973)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H301: Toxic if swallowed
Danger Acute toxicity, oral - Category 3 - H361: Suspected of damaging fertility or the unborn child
Warning Reproductive toxicity - Category 2 - H372: Causes damage to organs through prolonged or repeated exposure
Danger Specific target organ toxicity, repeated exposure - Category 1 - Hydralazine
- Apresoline
- Hydrazinophthalazine
- Apressoline
- Hydralazine mono-Hydrochloride
- Apressin
- Hydralazine mono Hydrochloride
- Hydrallazin
- Nepresol
-
SMILESC1=CC=C2C(=C1)C=NN=C2NN.Cl
-
InChIKeyZUXNZUWOTSUBMN-UHFFFAOYSA-N
- Pubchem - HYDRALAZINE HYDROCHLORIDE
- Wikipedia - hydralazine hydrochloride
Hydralazine, sold under the brand name Apresoline among others, is a medication used to treat high blood pressure and heart failure. This includes high blood pressure in pregnancy and very high blood pressure resulting in symptoms. It has been found to be particularly useful in heart failure together with isosorbide dinitrate in people of African descent.
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DIHYDRALAZINE
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1-chloro-4-hydrazinophthalazine
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4-fluoro-1H-indazol-3-amine
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4-chloro-1H-indazol-3-amine
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5-(Trifluoromethyl)-1H-indazol-3-amine
(2250-53-5)
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Benzo[c]cinnoline
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6-(trifluoromethyl)-1h-indazol-3-amine
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3-Aminopyridazine
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LUMINOL
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5-Aminoindazole
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1H-Indazol-7-amine
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1-Ethyl-1H-indazol-3-amine
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6-Bromophthalazine
(19064-74-5)
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3-hydrazino-6-phenylpyridazine
(38956-80-8)
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6-chloro-3-hydrazinylpyridazin-4-amine
(934-26-9)
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1-Chlorophthalazine
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3-methylcinnolin-5-amine
(300690-74-8)
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1H-Indazole-5,6-diamine
(7404-68-4)
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1,4-Dichlorophthalazine
(4752-10-7)
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1-Propyl-1H-indazol-3-amine
(108552-99-4)
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6-Aminoindazole
(6967-12-0)
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3-hydrazino-6-(4-methylphenyl)pyridazine
(18772-77-5)
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3-(4-chlorophenyl)-6-hydrazinopyridazine
(60478-25-3)
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4-Chloro-1-methyl-1H-indazol-3-amine
(959240-93-8)
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4-Hydrazinoquinazoline
(36075-44-2)
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1(2H)-PHTHALAZINONE
(62054-23-3, 119-39-1)
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(6653-91-4)
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(81115-45-9)
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1-Naphthylhydrazine
(2243-55-2)
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(2243-56-3)
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2-methyl-2H-indazol-5-amine
(60518-59-4)
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(1445-69-8)
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1-METHYL-1H-INDAZOL-5-AMINE
(50593-24-3)
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7-(trifluoromethyl)-1H-indazol-3-amine
(60330-35-0)
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2-Hydrazinoquinoline
(15793-77-8)
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(10071-13-3)
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(23687-25-4)
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(90223-02-2)
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6-bromoisoquinolin-3-amine
(891785-28-7)
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(5469-69-2)
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3-Amino-6-methylpyridazine
(18591-82-7)
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4-bromoisoquinolin-1-amine
(55270-27-4)
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(927802-22-0)
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(70724-25-3)
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(50593-30-1)
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1-methyl-1H-indazol-6-amine
(74728-65-7)
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1-Methyl-1H-indazol-4-amine
(77894-69-0)
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1H-Indazole
(271-44-3)
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4-Chloro-1-ethyl-1H-indazol-3-amine
(1015846-49-7)
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7-methyl-1H-indazol-5-amine
(844882-18-4)
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5-amino-2,3-dimethyl-2,3-dihydrophthalazine-1,4-dione
(873967-42-1)
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1-Chloro-4-methylphthalazine
(19064-68-7)
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1H-pyrrolo[3,2-c]pyridin-4-amine
(60290-23-5)
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2-hydrazino-4-methylquinoline
(21703-52-6)
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(15579-15-4)
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66612-29-1
(66612-29-1)
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2-Methyl-5-nitro-2H-indazole
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3-Hydrazinylquinoline
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4-methyl-1(2H)-phthalazinone
(5004-48-8)
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5-hydrazino-1-methyl-1H-pyrazole dihydrochloride
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quinazolin-4-ylamine
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1-Methyl-5-nitro-1H-indazole
(5228-49-9)
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2-Naphthylhydrazine hydrochloride
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Cinnolin-4-ol
(875-66-1)
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5-methyl-1H-indazole
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7-nitroindazole
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9-Hydrazinoacridine
(3407-93-0)
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8-Hydrazinoquinoline dihydrochloride hydrate
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59673-74-4
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1-bromoisoquinolin-3-amine
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3-Amino-6-methoxypyridazine
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6-methyl-5-nitro-1H-indazole
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4-Nitro-1H-indazole
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4-hydrazino-2-(trifluoromethyl)quinazoline
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6-hydrazino-3-methyl[1,2,4]triazolo[4,3-b]pyridazine
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9H-Carbazol-3-amine
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6-Bromo-N-methylpyridazin-3-amine
(1208657-07-1)
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6-chloro-N,N-dimethylpyridazin-3-amine
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HYDRALAZINE HYDROCHLORIDE
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