| Weight | 297.745 g/mol |
|---|---|
| Formula | C7H8ClN3O4S2 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
hydrochlorothiazide (58-93-5)
HydroDIURIL · HCTZ · Esidrix
Score:
#14 in Biochemistry
,
#102 in Biology
,
#104 in Chemistry
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- Benazepril plus Amlodipine or Hydrochlorothiazide for Hypertension in High-Risk Patients (The New England Journal of Medicine, 2008)
- A Comparison of the Effects of Hydrochlorothiazide and Captopril on Glucose and Lipid Metabolism in Patients with Hypertension (The New England Journal of Medicine, 1989)
- Comparative Antihypertensive Effects of Hydrochlorothiazide and Chlorthalidone on Ambulatory and Office Blood Pressure (Hypertension, 2006)
- Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide (Journal of Hypertension, 2007)
- Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipne ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension (American Journal of Cardiology, 1995)
- Hydrochlorothiazide Versus Chlorthalidone Evidence Supporting Their Interchangeability (Hypertension, 2004)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - HydroDIURIL
- HCTZ
- Esidrix
- Oretic
- Esidrex
- Dichlothiazide
- Hypothiazide
- Dihydrochlorothiazide
- Sectrazide
-
SMILESC1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl
-
InChIKeyJZUFKLXOESDKRF-UHFFFAOYSA-N
- Pubchem - hydrochlorothiazide
- Wikipedia - hydrochlorothiazide
Hydrochlorothiazide (HCTZ or HCT) is a diuretic medication often used to treat high blood pressure and swelling due to fluid build up. Other uses include diabetes insipidus, renal tubular acidosis, and to decrease the risk of kidney stones in those with high calcium level in the urine. For high blood pressure it is often recommended as a first line treatment.
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Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
Estimated Properties
| Density | 1.64 g/cm3 | EPA T.E.S.T. |
|---|---|---|
| Flash Point | 299.78 C | EPA T.E.S.T. |
| Water Solubility | 858.17 mg/L | EPA T.E.S.T. |
External Links
Synthesis
121-30-2
+
Reactant
(Alkylation of primary amines)
Similar Compounds
ETHIAZIDE
(1824-58-4)
10 alternate names
3 suppliers
121-30-2
(121-30-2)
10 alternate names
3 suppliers
102308-74-7
(102308-74-7)
10 alternate names
3 suppliers
671-89-6
(671-89-6)
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3 suppliers
2-AMINO-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE
(1269062-10-3)
10 alternate names
3 suppliers
2-amino-N-methylbenzenesulfonamide
(16288-77-0)
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3 suppliers
2-amino-N,N-dimethylbenzenesulfonamide
(54468-86-9)
10 alternate names
3 suppliers
3544-47-6
(3544-47-6)
10 alternate names
3 suppliers
74832-72-7
(74832-72-7)
10 alternate names
3 suppliers
2,5-dichloro-N,N-dimethylbenzenesulfonamide
(88522-19-4)
10 alternate names
3 suppliers
2,5-dichloro-n-methylbenzenesulfonamide
(6326-15-4)
10 alternate names
3 suppliers
81-10-7
(81-10-7)
10 alternate names
3 suppliers
233261-84-2
(233261-84-2)
10 alternate names
3 suppliers
4-chloro-2-nitrobenzenesulfonamide
(13852-81-8)
10 alternate names
3 suppliers
436095-29-3
(436095-29-3)
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3 suppliers
109902-09-2
(109902-09-2)
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3 suppliers
436095-30-6
(436095-30-6)
10 alternate names
3 suppliers
19818-06-5
(19818-06-5)
10 alternate names
3 suppliers
N-Methyl-2-nitrobenzenesulfonamide
(23530-40-7)
10 alternate names
3 suppliers
2,4,6-Trichlorobenzenesulfonamide
(28460-30-2)
10 alternate names
3 suppliers
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
(654-62-6)
10 alternate names
3 suppliers
2-Chloro-5-nitrobenzenesulfonamide
(96-72-0)
10 alternate names
3 suppliers
2,4,5-trichlorobenzenesulfonamide
(29092-27-1)
10 alternate names
3 suppliers
4-chloro-n-methyl-3-nitro-n-phenylbenzenesulfonamide
(6409-51-4)
10 alternate names
3 suppliers
54951-54-1
(54951-54-1)
10 alternate names
3 suppliers
N-cyclopropyl-2-nitrobenzenesulfonamide
(400839-43-2)
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3 suppliers
2,4,5-trichlorobenzenesulfonohydrazide
(6655-72-7)
10 alternate names
3 suppliers
107089-77-0
(107089-77-0)
10 alternate names
3 suppliers
2-Chlorobenzenesulfonamide
(6961-82-6)
10 alternate names
3 suppliers
23280-39-9
(23280-39-9)
10 alternate names
3 suppliers
301331-16-8
(301331-16-8)
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3 suppliers
5-Chloro-2-nitrobenzenesulfonamide
(68379-05-5)
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3 suppliers
22663-37-2
(22663-37-2)
10 alternate names
3 suppliers
2,5-dichlorobenzenesulfonamide
(7720-45-8)
10 alternate names
3 suppliers
2080-32-2
(2080-32-2)
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3 suppliers
35974-23-3
(35974-23-3)
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3 suppliers
13480-70-1
(13480-70-1)
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3 suppliers
4-amino-N-methyl-N-phenylbenzenesulfonamide
(63826-12-0)
10 alternate names
3 suppliers
2,5-dichlorobenzenesulfonohydrazide
(6775-66-2)
10 alternate names
3 suppliers
2-amino-5-bromobenzenesulfonamide
(54734-84-8)
10 alternate names
3 suppliers
21626-69-7
(21626-69-7)
10 alternate names
3 suppliers
XIPAMIDE
(14293-44-8)
10 alternate names
3 suppliers
35959-60-5
(35959-60-5)
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3 suppliers
n-(3,5-dimethylphenyl)-n-(phenylsulfonyl)glycine
(5628-64-8)
10 alternate names
3 suppliers
N-(furan-2-ylmethyl)-2-nitrobenzenesulfonamide
(303063-01-6)
10 alternate names
3 suppliers
288154-64-3
(288154-64-3)
10 alternate names
3 suppliers
4-amino-N-ethyl-N-phenylbenzenesulfonamide
(50497-33-1)
10 alternate names
3 suppliers
793677-83-5
(793677-83-5)
10 alternate names
3 suppliers
2-Aminobenzenesulfonamide
(3306-62-5)
10 alternate names
3 suppliers
117309-41-8
(117309-41-8)
10 alternate names
3 suppliers
425680-38-2
(425680-38-2)
10 alternate names
3 suppliers
100318-71-6
(100318-71-6)
10 alternate names
3 suppliers
7478-88-8
(7478-88-8)
10 alternate names
3 suppliers
5702-82-9
(5702-82-9)
10 alternate names
3 suppliers
20491-97-8
(20491-97-8)
10 alternate names
3 suppliers
Carbutamide
(339-43-5)
10 alternate names
3 suppliers
Piperazine, 1-[(4-aminophenyl)sulfonyl]-4-phenyl-
(150558-10-4)
10 alternate names
3 suppliers
2,4-Dichloro-5-sulfamoylbenzoic acid
(2736-23-4)
10 alternate names
3 suppliers
16879-68-8
(16879-68-8)
10 alternate names
3 suppliers
Succinylsulfacetamide
(3811-16-3)
10 alternate names
3 suppliers
335208-47-4
(335208-47-4)
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3 suppliers
314744-44-0
(314744-44-0)
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3 suppliers
41608-75-7
(41608-75-7)
10 alternate names
3 suppliers
Dansylcadaverine
(10121-91-2)
10 alternate names
3 suppliers
2-Nitrobenzenesulfonamide
(5455-59-4)
10 alternate names
3 suppliers
4-[(4-BENZHYDRYL-1-PIPERAZINYL)SULFONYL]ANILINE
(20127-97-3)
10 alternate names
3 suppliers
4-Amino-N,N-dimethylbenzenesulfonamide
(1709-59-7)
10 alternate names
3 suppliers
4-chloro-3-nitro-5-sulfamoylbenzoic acid
(22892-96-2)
10 alternate names
3 suppliers
4-Chloro-N-methylbenzenesulfonamide
(6333-79-5)
10 alternate names
3 suppliers
26638-53-9
(26638-53-9)
10 alternate names
3 suppliers
2-Amino-4-chloro-5-methylbenzenesulfonic acid
(88-51-7)
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3 suppliers
N,N-diallyl-4-aminobenzenesulfonamide
(193891-96-2)
10 alternate names
3 suppliers
4-(3,4-dihydroquinolin-1(2H)-ylsulfonyl)aniline
(5455-89-0)
10 alternate names
3 suppliers
4-Amino-N,N-diethylbenzenesulfonamide
(1709-39-3)
10 alternate names
3 suppliers
4-thioureidobenzenesulfonamide
(1718-39-4)
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3 suppliers
Chlorimuron ethyl
(90982-32-4, 94365-91-0)
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3 suppliers
26638-66-4
(26638-66-4)
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3 suppliers
4-(Morpholinosulfonyl)aniline
(21626-70-0)
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3 suppliers
4-amino-N-benzyl-N-methylbenzenesulfonamide
(108622-87-3)
10 alternate names
3 suppliers
4-Amino-N-methylbenzenesulfonamide
(1709-52-0)
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3 suppliers
51123-09-2
(51123-09-2)
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3 suppliers
26723-60-4
(26723-60-4)
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3 suppliers
benzoic acid, 2-[methyl[(4-methylphenyl)sulfonyl]amino]-
(19577-80-1)
10 alternate names
3 suppliers
4-Chloro-2-nitrophenyl methyl sulfone
(2163-97-5)
10 alternate names
3 suppliers
AC1LHH2S
(109069-00-3)
10 alternate names
3 suppliers
4-[(2-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]aniline
(774586-92-4)
10 alternate names
3 suppliers
3-amino-4-chlorobenzenesulfonamide
(29092-34-0)
10 alternate names
3 suppliers
4-(Aminosulfonyl)-5-chlorophthalimide
(3861-99-2)
10 alternate names
3 suppliers
1024-30-2
(1024-30-2)
10 alternate names
3 suppliers
4-amino-N-(3-chlorophenyl)benzenesulfonamide
(19837-81-1)
10 alternate names
3 suppliers
70176-69-1
(70176-69-1)
10 alternate names
3 suppliers
4-(2,3-dihydro-1H-indol-1-ylsulfonyl)aniline
(314284-67-8)
10 alternate names
3 suppliers
4-amino-N,N-dipropylbenzenesulfonamide
(21646-92-4)
10 alternate names
3 suppliers
hydrochlorothiazide
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