| Weight | 420.093 g/mol |
|---|---|
| Formula | C6H15O15P3 |
| Hydrogen Acceptors | 9 |
| Hydrogen Donors | 9 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 6 |
inositol 1,4,5-trisphosphate (85166-31-0, 88269-39-0)
Score:
#44 in Molecular and cellular biology
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#777 in Neuroscience
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#1440 in Biochemistry
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#3413 in Biology
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- Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate. (Nature, 1983)
- Range of messenger action of calcium ion and inositol 1,4,5-trisphosphate (Science, 1992)
- Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400 (Nature, 1989)
- Calcium as a coagonist of inositol 1,4,5-trisphosphate-induced calcium release (Science, 1991)
- Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes. (Nature, 1987)
- Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions (Proceedings of the National Academy of Sciences of the United States of America, 1989)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1(C(C(C(C(C1OP(=O)(O)O)O)OP(=O)(O)O)OP(=O)(O)O)O)O
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InChIKeyMMWCIQZXVOZEGG-UHFFFAOYSA-N
- Pubchem - inositol 1,4,5-trisphosphate
- Wikipedia - Inositol trisphosphate
Inositol trisphosphate or inositol 1,4,5-trisphosphate (also commonly known as triphosphoinositol; abbreviated InsP3 or Ins3P or IP3), together with diacylglycerol (DAG), is a secondary messenger molecule used in signal transduction and lipid signaling in biological cells. While DAG stays inside the membrane, IP3 is soluble and diffuses through the cell. It is made by hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2), a phospholipid that is located in the plasma membrane, by phospholipase C (PLC).
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