ketoprofen (22071-15-4)

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Suppliers

• Sigma-Aldrich - ketoprofen
  45.10 - 982.00 USD
• Fisher Scientific - Search for ketoprofen
• TCI - ketoprofen
  129.00 - 746.00 USD

Most-cited Publications

• Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters. (Environmental Science & Technology, 2003)
• Transdermal delivery of ketoprofen using microemulsions (International Journal of Pharmaceutics, 2001)
• CLINICAL AND PHARMACOKINETIC EVIDENCE OF A LIFE-THREATENING INTERACTION BETWEEN METHOTREXATE AND KETOPROFEN (The Lancet, 1986)
• Comparison of adverse effects of phenylbutazone, flunixin meglumine, and ketoprofen in horses (Javma-journal of The American Veterinary Medical Association, 1993)
• Clinical Pharmacokinetics of Ketoprofen and Its Enantiomers (Clinical Pharmacokinectics, 1990)
• Ketoprofen: A Review of Its Pharmacologic and Clinical Properties (Pharmacotherapy, 1986)

Areas of Application

Safety

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Trends

Alternate Names

• Orudis
• Benzoylhydratropic Acid
• RP-19583
• Alrheumat
• 2-(3-Benzoylphenyl)propionic Acid
• Alrheumum
• 19,583 RP
• RP19583
• RP 19583
• Profenid
• SMILES
  CC(C1=CC=CC(=C1)C(=O)C2=CC=CC=C2)C(=O)O
• InChIKey
  DKYWVDODHFEZIM-UHFFFAOYSA-N

External Links

• Pubchem - ketoprofen
• Wikipedia - ketoprofen
  Ketoprofen, (RS)-2-(3-benzoylphenyl)-propionic acid (chemical formula C16H14O3) is one of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin. As of 2015 the cost for a typical month of medication in the United States is 50 to 100 USD.

Synthesis

Reactant  +  CHLOROBENZENE (Grignard carbonyl)

Reactant  +  BENZOYL CHLORIDE (Suzuki)

Synthesis of ketoprofen ›

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