Score: #303 in Neuroscience , #398 in Biochemistry , #1366 in Biology , #1598 in Chemistry

  Analgesic · Antianginal · Antiarrhythmic agent · Antidepressant · Antihypertensive agent · Calcium channel blocker · Delta-opioid agonist · Dissociative drug · Drugs acting on the cardiovascular system · Drugs acting on the nervous system · Drugs acting on the respiratory system · Drugs by psychological effect · Euphoriant · GABA receptor antagonist · GABA receptor ligand · Kappa agonist · Monoamine reuptake inhibitor · Mu-opioid agonist · Nociceptin receptor agonist · Opioid receptor ligand · Opioid · Pharmaceutical · Psychoactive drug · Psychoactive drugs by mechanism of action · Psychopharmacology · Respiratory system drug · Serotonin-norepinephrine reuptake inhibitor · Synthetic opioid

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• Sigma-Aldrich - Search for levorphanol
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Most-cited Publications

• Stereospecific and Nonspecific Interactions of the Morphine Congener Levorphanol in Subcellular Fractions of Mouse Brain (Proceedings of the National Academy of Sciences of the United States of America, 1971)
• Dextrorphan and levorphanol selectively block N-methyl-D-aspartate receptor-mediated neurotoxicity on cortical neurons. (Journal of Pharmacology and Experimental Therapeutics, 1987)
• Differential effects of dextrorphan and levorphanol on the excitation of rat spinal neurons by amino acids. (European Journal of Pharmacology, 1985)
• Effects of butorphanol, flunixin, levorphanol, morphine, and xylazine in ponies. (American Journal of Veterinary Research, 1984)
• TOLERANCE TO OPIOID NARCOTICS. I. TOLERANCE TO THE "RUNNING FIT" CAUSED BY LEVORPHANOL IN THE MOUSE (Journal of Pharmacology and Experimental Therapeutics, 1969)
• Comparative pharmacology of levorphan, racemorphan and dextrorphan and related methyl ethers. (Journal of Pharmacology and Experimental Therapeutics, 1953)

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Alternate Names

• Levorphanol Tartrate
• Levorphan
• LevoDromoran
• ICN Brand of Levorphanol Tartrate
• 3-Hydroxy-N-methylmorphinan
• Levo Dromoran
• Levodroman
• 3 Hydroxy N methylmorphinan
• L Dromoran
• Levo-Dromoran
• L-Dromoran
• SMILES
  CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)O
• InChIKey
  JAQUASYNZVUNQP-UHFFFAOYSA-N

External Links

• Pubchem - levorphanol
• Wikipedia - levorphanol
  Levorphanol (INN; brand name Levo-Dromoran) is an opioid medication used to treat moderate to severe pain. It is one of four enantiomers of the compound racemorphan, and was first described in Germany in 1948 as an orally active, morphine-like analgesic. The drug has been in clinical use in the United States since 1953.

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