Weight | 254.289 g/mol |
---|---|
Formula | C15H14N2O2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 2 |
Aromatic Rings | 2 |
Rotatable Bonds | 0 |
Licarbazepine (29331-92-8)
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- Sigma-Aldrich - Licarbazepine98.00 - 692.00 USD
- Fisher Scientific - Search for Licarbazepine
- TCI - Search for Licarbazepine
- First HPLC-UV method for rapid and simultaneous quantification of phenobarbital, primidone, phenytoin, carbamazepine, carbamazepine-10,11-epoxide, 10,11-trans-dihydroxy-10,11-dihydrocarbamazepine, lamotrigine, oxcarbazepine and licarbazepine in human plasma. (Journal of Chromatography B, 2013)
- Simultaneous and enantioselective liquid chromatographic determination of eslicarbazepine acetate, S-licarbazepine, R-licarbazepine and oxcarbazepine in mouse tissue samples using ultraviolet detection (Analytica Chimica Acta, 2007)
- Liquid chromatographic assay based on microextraction by packed sorbent for therapeutic drug monitoring of carbamazepine, lamotrigine, oxcarbazepine, phenobarbital, phenytoin and the active metabolites carbamazepine-10,11-epoxide and licarbazepine (Journal of Chromatography B, 2014)
- Development and validation of an enantioselective liquid-chromatography/tandem mass spectrometry method for the separation and quantification of eslicarbazepine acetate, eslicarbazepine, R-licarbazepine and oxcarbazepine in human plasma. (Journal of Chromatography B, 2011)
- Binding of licarbazepine enantiomers to mouse and human plasma proteins. (Biopharmaceutics & Drug Disposition, 2010)
- A chiral liquid chromatography method for the simultaneous determination of oxcarbazepine, eslicarbazepine, Rlicarbazepine and other new chemical derivatives BIA 2024, BIA 2059 and BIA 2265, in mouse plasma and brain (Biomedical Chromatography, 2011)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1C(C2=CC=CC=C2N(C3=CC=CC=C31)C(=O)N)O
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InChIKeyBMPDWHIDQYTSHX-UHFFFAOYSA-N
- Pubchem - Licarbazepine
- Wikipedia - licarbazepine
Licarbazepine is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects that is related to oxcarbazepine. It is an active metabolite of oxcarbazepine. In addition, an isomer of licarbazepine, eslicarbazepine ((S)-(+)-licarbazepine), is an active metabolite of eslicarbazepine acetate.
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