| Weight | 340.492 g/mol |
|---|---|
| Formula | C20H24N2OS |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 6 |
LUCANTHONE (479-50-5, 548-57-2)
Miracil D · Lucanthone Hydrochloride · Tixantone
Score:
#282 in Microbiology
,
#934 in Biochemistry
,
#2467 in Biology
,
#3078 in Chemistry
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- Inhibition of the human apurinic/apyrimidinic endonuclease (Ape1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone (Anticancer Research, 2004)
- A new active metabolite of "Miracil D". (Nature, 1965)
- Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis (Journal of Biological Chemistry, 2011)
- Hycanthone, a new active metabolite of lucanthone. (Journal of Medicinal Chemistry, 1967)
- Modification of the heat response and thermotolerance by cycloheximide, hydroxyurea, and lucanthone in CHO cells (Radiation Research, 1982)
- Enhancement of x-ray damage in HeLa cells by exposure to lucanthone (Miracil D) following radiation. (Cancer Research, 1970)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Miracil D
- Lucanthone Hydrochloride
- Tixantone
-
SMILESCCN(CC)CCNC1=C2C(=C(C=C1)C)SC3=CC=CC=C3C2=O
-
InChIKeyFBQPGGIHOFZRGH-UHFFFAOYSA-N
- Pubchem - LUCANTHONE
- Wikipedia - lucanthone
Lucanthone is a drug used in chemotherapy. It is a prodrug and is converted to the active metabolite hycanthone.
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