Weight | 203.757 g/mol |
---|---|
Formula | C11H22ClN |
Hydrogen Acceptors | 1 |
Hydrogen Donors | 1 |
Aromatic Rings | 0 |
Rotatable Bonds | 1 |
MECAMYLAMINE HYDROCHLORIDE (826-39-1)
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- GANGLIONIC BLOCKING PROPERTIES OF 3-METHYLAMINOISOCAMPHANE HYDROCHLORIDE (MECAMYLAMINE): A SECONDARY AMINE (Journal of Pharmacology and Experimental Therapeutics, 1956)
- Renal elimination of 3-methylaminoisocamphane hydrochloride (mecamylamine). (American Journal of Physiology, 1956)
- GASTROINTESTINAL SECRETION AND ABSORPTION OF 3-METHYLAMINOISOCAMPHANE HYDROCHLORIDE (MECAMYLAMINE) (Journal of Pharmacology and Experimental Therapeutics, 1958)
- [Experimental & clinical observation on the activity of a new synthetic ganglioplegic: mecamylamine (3-methylaminoisocamphane hydrochloride)]. (Minerva Medica, 1958)
- Ileus due to mecamylamine hydrochloride; simulating an acute surgical condition of the abdomen. (Minnesota medicine, 1958)
- [Experiments with a new ganglion-blocking agent, mecamylamine hydrochloride in the treatment of arterial hypertension]. (Archivos del Instituto de Cardiologia de Mexico, 1957)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1(C2CCC(C2)C1(C)NC)C.Cl
-
InChIKeyPKVZBNCYEICAQP-UHFFFAOYSA-N
- Pubchem - MECAMYLAMINE HYDROCHLORIDE
- Wikipedia - mecamylamine hydrochloride
Mecamylamine (INN, BAN; or mecamylamine hydrochloride (USAN); brand names Inversine, Vecamyl) is a non-selective, non-competitive antagonist of the nicotinic acetylcholine receptors (nAChRs) that was introduced in the 1950s as an antihypertensive drug. In the United States, it was voluntarily withdrawn from the market in 2009 but was brought to market in 2013 as Vecamyl and eventually was marketed by Turing Pharmaceuticals. Chemically, mecamylamine is a secondary aliphatic amine, with a pKaH of 11.2
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