Weight | 215.724 g/mol |
---|---|
Formula | C11H18ClNO |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 3 |
Mexiletine hydrochloride (5370-01-4)
Mexiletine · Mexitil · Mexiletene
Score:
#180 in Neurology
,
#810 in Neuroscience
,
#3558 in Biology
,
#4466 in Chemistry
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- Sodium Channel Block With Mexiletine Is Effective in Reducing Dispersion of Repolarization and Preventing Torsade de Pointes in LQT2 and LQT3 Models of the Long-QT Syndrome (Circulation, 1997)
- MEXILETINE FOR TREATMENT OF CHRONIC PAINFUL DIABETIC NEUROPATHY (The Lancet, 1988)
- The analgesic effect of gabapentin and mexiletine after breast surgery for cancer. (Anesthesia & Analgesia, 2002)
- New antiarrhythmic agents: amiodarone, aprindine, disopyramide, ethmozin, mexiletine, tocainide, verapamil. (American Journal of Cardiology, 1978)
- The effect of intravenous lidocaine, tocainide, and mexiletine on spontaneously active fibers originating in rat sciatic neuromas (Pain, 1989)
- A randomized trial of amitriptyline and mexiletine for painful neuropathy in HIV infection (Neurology, 1998)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Mexiletine
- Mexitil
- Mexiletene
- Mexityl
- KOE-1173
- KO1173
- KOE 1173
- Novo-Mexiletine
- KO-1173
- Novo Mexiletine
- Mexitil PL
- KOE1173
- KO 1173
-
SMILESCC1=C(C(=CC=C1)C)OCC(C)N.Cl
-
InChIKeyNFEIBWMZVIVJLQ-UHFFFAOYSA-N
- Pubchem - Mexiletine hydrochloride
- Wikipedia - mexiletine hydrochloride
Mexiletine (INN) (sold under the trade name Mexitil) is a non-selective voltage-gated sodium channel blocker which belongs to the Class IB anti-arrhythmic group of medicines. It is used to treat arrhythmias within the heart, or seriously irregular heartbeats. It slows conduction in the heart and makes the heart tissue less sensitive.
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