| Weight | 169.18 g/mol |
|---|---|
| Formula | C8H11NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
oxidopamine (1199-18-4)
6 Hydroxydopamine · 6-Hydroxydopamine · 6-OHDA
Score:
#721 in Neuroscience
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#3187 in Biology
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#3987 in Chemistry
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- Adipsia and Aphagia after 6-Hydroxydopamine Induced Degeneration of the Nigro-striatal Dopamine System (Acta Physiologica Scandinavica, 1971)
- Autoxidation versus Covalent Binding of Quinones as the Mechanism of Toxicity of Dopamine, 6-Hydroxydopamine, and Related Compounds toward C1300 Neuroblastoma Cells in Vitro (Molecular Pharmacology, 1978)
- The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and related cytotoxic agents. (Journal of Biological Chemistry, 1974)
- Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-hydroxydopamine (Naunyn-schmiedebergs Archives of Pharmacology, 1968)
- Pharmacological Actions of 6-Hydroxydopamine (Pharmacological Reviews, 1974)
- Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens (Pharmacology, Biochemistry and Behavior, 1980)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 6 Hydroxydopamine
- 6-Hydroxydopamine
- 6-OHDA
- Oxidopamine Hydrochloride
- Oxidopamine Hydrobromide
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SMILESC1=C(C(=CC(=C1O)O)O)CCN
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InChIKeyDIVDFFZHCJEHGG-UHFFFAOYSA-N
- Pubchem - oxidopamine
- Wikipedia - oxidopamine
Oxidopamine, also known as 6-hydroxydopamine (6-OHDA) or 2,4,5-trihydroxyphenethylamine, is a neurotoxic synthetic organic compound used by researchers to selectively destroy dopaminergic and noradrenergic neurons in the brain. 6-OHDA is thought to enter the neurons via the dopamine and noradrenaline (norepinephrine) reuptake transporters. Oxidopamine is often used in conjunction with a selective noradrenaline reuptake inhibitor (such as desipramine) to selectively destroy dopaminergic neurons.
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