| Weight | 211.224 g/mol |
|---|---|
| Formula | C12H9N3O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 1 |
milrinone (78415-72-2)
Primacor · Milrinone Lactate · Win 47203
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#2804 in Biology
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#3510 in Chemistry
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- Sigma-Aldrich - milrinone226.50 - 724.00 USD
- Fisher Scientific - Search for milrinone
- TCI - milrinone88.00 - 495.00 USD
- Effect of Oral Milrinone on Mortality in Severe Chronic Heart Failure (The New England Journal of Medicine, 1991)
- Short-term intravenous milrinone for acute exacerbation of chronic heart failure: A randomized controlled trial (JAMA, 2002)
- Efficacy and Safety of Milrinone in Preventing Low Cardiac Output Syndrome in Infants and Children After Corrective Surgery for Congenital Heart Disease (Circulation, 2003)
- A comparison of oral milrinone, digoxin, and their combination in the treatment of patients with chronic heart failure. (The New England Journal of Medicine, 1989)
- Lower Serum Sodium Is Associated With Increased Short-Term Mortality in Hospitalized Patients With Worsening Heart Failure Results From the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) Study (Circulation, 2005)
- Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study. (Journal of the American College of Cardiology, 2003)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Primacor
- Milrinone Lactate
- Win 47203
- Sanofi Winthrop Brand of Milrinone Lactate
- Corotrope
- Corotrop
- Sanofi Brand of Milrinone Lactate
- Win-47203
- Sanofi Synthelabo Brand of Milrinone
- Win47203
- Sanofi Synthelabo Brand of Milrinone Lactate
-
SMILESCC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2
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InChIKeyPZRHRDRVRGEVNW-UHFFFAOYSA-N
- Pubchem - milrinone
- Wikipedia - milrinone
Milrinone, commonly known and marketed under the brand name Primacor, is a medication used in patients who have heart failure. It is a phosphodiesterase 3 inhibitor that works to increase the heart's contractility and decrease pulmonary vascular resistance. Milrinone also works to vasodilate which helps alleviate increased pressures (afterload) on the heart, thus improving its pumping action.
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Synthesis
ISONICOTINIC ACID
+
Reactant
(Decarboxylative coupling)
4-BROMOPYRIDINE
+
Reactant
(Stille)
Reactant
+
4-CHLOROPYRIDINE
(Suzuki)
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milrinone
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