| Weight | 241.682 g/mol |
|---|---|
| Formula | C9H12ClN5O |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
MOXONIDINE (75438-57-2)
Moxon · Zint · Cynt
Score:
#774 in Neuroscience
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#3407 in Biology
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- Adverse mortality effect of central sympathetic inhibition with sustained-release moxonidine in patients with heart failure (MOXCON) (European Journal of Heart Failure, 2003)
- Moxonidine, a centrally acting antihypertensive agent, is a selective ligand for I1-imidazoline sites. (Journal of Pharmacology and Experimental Therapeutics, 1993)
- Moxonidine : a review of its pharmacology, and therapeutic use in essential hypertension (Drugs, 1992)
- Assumption testing in population pharmacokinetic models: illustrated with an analysis of moxonidine data from congestive heart failure patients. (Journal of Pharmacokinetics and Biopharmaceutics, 1998)
- Arteriolar wall thickening, capillary rarefaction and interstitial fibrosis in the heart of rats with renal failure:the effects of ramipril, nifedipine and moxonidine. (Journal of The American Society of Nephrology, 1996)
- Moxonidine treatment of hypertensive patients with advanced renal failure. (Journal of Hypertension, 2003)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Moxon
- Zint
- Cynt
- 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine
- moxonidin
- BE-5895
- Solvay brand of moxonidine
- Physiotens
- Lilly brand of moxonidine
- Normatens
- BE 5895
-
SMILESCC1=NC(=C(C(=N1)Cl)NC2=NCCN2)OC
-
InChIKeyWPNJAUFVNXKLIM-UHFFFAOYSA-N
- Pubchem - MOXONIDINE
- Wikipedia - moxonidine
Moxonidine (INN) is a new-generation centrally acting antihypertensive drug licensed for the treatment of mild to moderate essential hypertension. It may have a role when thiazides, beta-blockers, ACE inhibitors and calcium channel blockers are not appropriate or have failed to control blood pressure. In addition, it demonstrates favourable effects on parameters of the insulin resistance syndrome, apparently independent of blood pressure reduction.
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