| Weight | 232.239 g/mol |
|---|---|
| Formula | C12H12N2O3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
nalidixic acid (389-08-2)
Nalidixate Sodium Anhydrous · Nevigramon · Nalidixin
Score:
#184 in Microbiology
,
#1891 in Biology
,
#2279 in Chemistry
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- Nalidixic acid resistance: a second genetic character involved in DNA gyrase activity. (Proceedings of the National Academy of Sciences of the United States of America, 1977)
- Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme (Proceedings of the National Academy of Sciences of the United States of America, 1977)
- Mechanism of inhibition of DNA gyrase by analogues of nalidixic acid: the target of the drugs is DNA (Proceedings of the National Academy of Sciences of the United States of America, 1985)
- Mechanism of Action of Nalidixic Acid on Escherichia coli II. Inhibition of Deoxyribonucleic Acid Synthesis (Journal of Bacteriology, 1965)
- MECHANISM OF ACTION OF NALIDIXIC ACID ON ESCHERICHIA COLI (Journal of Bacteriology, 1964)
- Isolation and Molecular Characterization of Nalidixic Acid-Resistant Extraintestinal Pathogenic Escherichia coli from Retail Chicken Products (Antimicrobial Agents and Chemotherapy, 2003)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Nalidixate Sodium Anhydrous
- Nevigramon
- Nalidixin
- Sodium Nalidixic Acid, Anhydrous
- Sodium Nalidixic Acid, Monohydrate
- Nalidixate Sodium
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SMILESCCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O
-
InChIKeyMHWLWQUZZRMNGJ-UHFFFAOYSA-N
- Pubchem - nalidixic acid
- Wikipedia - nalidixic acid
Nalidixic acid (tradenames Nevigramon, Neggram, Wintomylon and WIN 18,320) is the first of the synthetic quinolone antibiotics. In a technical sense, it is a naphthyridone, not a quinolone: its ring structure is a 1,8-naphthyridine nucleus that contains two nitrogen atoms, unlike quinoline, which has a single nitrogen atom. Synthetic quinolone antibiotics were discovered by George Lesher and coworkers as a byproduct of chloroquine manufacture in the 1960s.
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nalidixic acid
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