Weight | 284.098 g/mol |
---|---|
Formula | C12H7Cl2NO3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 0 |
Aromatic Rings | 2 |
Rotatable Bonds | 3 |
Nitrofen (1836-75-5)
TOK · nitrophen · nitrafen
Score:
#289 in Physics
,
#752 in Biology
,
#824 in Chemistry
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- Dual-hit hypothesis explains pulmonary hypoplasia in the nitrofen model of congenital diaphragmatic hernia. (American Journal of Pathology, 2000)
- Nitrofen-induced diaphragmatic hernias in rats : an animal model (Journal of Pediatric Surgery, 1990)
- Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001 (Nature, 2012)
- The Origins of Syntax in Discourse: A Case Study of Tok Pisin Relatives (Language, 1976)
- The heart and diaphragm: target organs in the neonatal death induced by nitrofen (2,4-dichlorophenyl-p-nitrophenyl ether). (Toxicology, 1981)
- Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic hernia in rats. (American Journal of Physiology-lung Cellular and Molecular Physiology, 1999)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - H315: Causes skin irritation
Warning Skin corrosion/irritation - Category 2 - H319: Causes serious eye irritation
Warning Serious eye damage/eye irritation - Category 2A - H351: Suspected of causing cancer
Warning Carcinogenicity - Category 2 - H360: May damage fertility or the unborn child
Danger Reproductive toxicity - Category 1A, 1B - H372: Causes damage to organs through prolonged or repeated exposure
Danger Specific target organ toxicity, repeated exposure - Category 1 - H410: Very toxic to aquatic life with long lasting effects
Warning Hazardous to the aquatic environment, long-term hazard - Category 1 - TOK
- nitrophen
- nitrafen
- 2,4-dichlorophenyl-4-nitrophenyl ether
- 1,3-dichlorophenyl-p-nitrophenyl ether
- nitrochlor
-
SMILESC1=CC(=CC=C1[N+](=O)[O-])OC2=C(C=C(C=C2)Cl)Cl
-
InChIKeyXITQUSLLOSKDTB-UHFFFAOYSA-N
- Pubchem - Nitrofen
- Wikipedia - nitrofen
Nitrofen is an herbicide of the diphenyl ether class. Because of concerns about its carcinogenicity, the use of nitrofen has been banned in the European Union and in the United States since 1996. In 2002 Nitrofen was detected in organic feed, organic eggs, and organic poultry products in Germany prompting a scandal which caused a decline in all organic meat sales in Europe to slip.
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Synthesis
4-nitrobenzaldehyde
+
Reactant
(Dakin oxidation)
Similar Compounds
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(3273-78-7)
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(89-64-5)
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(28987-59-9)
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(63707-35-7)
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(39224-65-2)
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(610-78-6)
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(61702-43-0)
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(6082-87-7)
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(99-53-6)
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(121-27-7)
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(93-67-4)
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(99-30-9, 81859-29-2)
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(16365-27-8)
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methyl 4-[(2-chloro-4-nitrophenoxy)methyl]benzoate
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4-(2,4-dinitrophenoxy)benzaldehyde
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54306-27-3
(54306-27-3)
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4-Amino-2-chlorophenol
(3964-52-1)
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3-chloro-5-nitroaniline
(5344-44-5)
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5-Amino-2,4-dichlorophenol
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2-Methyl-4-nitroanisole
(50741-92-9)
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4-BROMO-2-CHLORO-6-NITROPHENOL
(58349-01-2)
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3-methoxy-4-(4-nitrophenoxy)benzaldehyde
(166904-09-2)
7 alternate names
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