| Weight | 238.334 g/mol |
|---|---|
| Formula | C16H18N2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 1 |
Nomifensine (24526-64-5, 89664-20-0)
Merital · Nomifensine Maleate · Nomifensine Maleate (1:1)
Score:
#428 in Neuroscience
,
#1964 in Biology
,
#2390 in Chemistry
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- Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats (Neuroscience, 1989)
- Dopamine can be released by two mechanisms differentially affected by the dopamine transport inhibitor nomifensine. (Journal of Pharmacology and Experimental Therapeutics, 1979)
- Nomifensine: a new potent inhibitor of dopamine uptake into synaptosomes from rat brain corpus striatum (Journal of Pharmacy and Pharmacology, 1974)
- Extracellular dopamine in rat striatum following uptake inhibition by cocaine, nomifensine and benztropine. (European Journal of Pharmacology, 1987)
- The acquisition of responding with conditioned reinforcement: effects of pipradrol, methylphenidate, d-amphetamine, and nomifensine. (Psychopharmacology, 1978)
- Habit-forming actions of nomifensine in nucleus accumbens (Psychopharmacology, 1995)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Merital
- Nomifensine Maleate
- Nomifensine Maleate (1:1)
- Linamiphen
- Nomifensin
- Hoe 984
- Hoe984
- Hoe-984
-
SMILESCN1CC(C2=C(C1)C(=CC=C2)N)C3=CC=CC=C3
-
InChIKeyXXPANQJNYNUNES-UHFFFAOYSA-N
- Pubchem - Nomifensine
- Wikipedia - nomifensine
Nomifensine (Merital, Alival) is a norepinephrine-dopamine reuptake inhibitor, i.e. a drug that increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters. This is a mechanism of action shared by some recreational drugs like cocaine and the medication tametraline (see DRI).
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