| Weight | 223.319 g/mol |
|---|---|
| Formula | C16H17N |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
1-Benzyl-1,2,3,4-tetrahydroisoquinoline (19716-56-4)
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- 1Benzyl1,2,3,4Tetrahydroisoquinoline as a ParkinsonismInducing Agent: A Novel Endogenous Amine in Mouse Brain and Parkinsonian CSF (Journal of Neurochemistry, 2002)
- Chronic administration of 1-benzyl-1,2,3,4-tetrahydroisoquinoline, an endogenous amine in the brain, induces parkinsonism in a primate (Neuroscience Letters, 1996)
- 1-Benzyl-1,2,3,4-tetrahydroisoquinoline, a Parkinsonism-inducing endogenous toxin, increases -synuclein expression and causes nuclear damage in human dopaminergic cells (Journal of Neuroscience Research, 2004)
- Biochemical and pathological study of endogenous 1-benzyl-1,2,3,4-tetrahydroisoquinoline-induced parkinsonism in the mouse. (Brain Research, 2001)
- Neurotoxicity of an endogenous brain amine, 1-benzyl-1,2,3,4-tetrahydroisoquinoline, in organotypic slice co-culture of mesencephalon and striatum (Neuroscience, 2003)
- Deprenyl decreases an endogenous parkinsonism-inducing compound, 1-benzyl-1,2,3,4-tetrahydroisoquinoline in mice: in vivo and in vitro studies. (Brain Research, 1998)
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SMILESC1CNC(C2=CC=CC=C21)CC3=CC=CC=C3
-
InChIKeyYRYCIFUZSUMAAY-UHFFFAOYSA-N
- Pubchem - 1-Benzyl-1,2,3,4-tetrahydroisoquinoline
- Wikipedia - 1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline
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Synthesis
Phenethylamine
+
Reactant
(Alkylation of primary amines)
Reactant
+
CID 5477119
(Chan-Lam coupling reaction)
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