Orotic acid (65-86-1)

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  100 g
  $145.00

  500 g
  $406.00

Most-cited Publications

• A positive selection for mutants lacking orotidine-5-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance (Molecular Genetics and Genomics, 1984)
• An enzymatic spectrophotometric method for determination of orotic acid. (Journal of Laboratory and Clinical Medicine, 1964)
• Total Inhibition of Hepatic -Lipoprotein Production in the Rat by Orotic Acid (Journal of Biological Chemistry, 1967)
• Refractory Megaloblastic Anemia Associated with Excretion of Orotic Acid (Blood, 1959)
• PERFUSION IN SITU WITH TRITIUM OXIDE TO MEASURE HEPATIC LIPOGENESIS AND LIPID SECRETION: NORMAL AND OROTIC ACID-FED RATS (Journal of Biological Chemistry, 1966)
• A SURVEY OF THE METABOLISM OF OROTIC ACID IN THE RAT (Journal of Biological Chemistry, 1952)

Areas of Application

Safety

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  Predict GHS Hazards for Any Chemical in silico.
  Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more.
• H302: Harmful if swallowed
  Warning Acute toxicity, oral - Category 4

Trends

Alternate Names

• Zinc Orotate
• Potassium Orotate
• Sodium Orotate
• SMILES
  C1=C(NC(=O)NC1=O)C(=O)O
• InChIKey
  PXQPEWDEAKTCGB-UHFFFAOYSA-N

External Links

• Pubchem - Orotic acid
• Wikipedia - orotic acid
  Orotic acid is a heterocyclic compound and an acid; it is also known as pyrimidinecarboxylic acid. Historically it was believed to be part of the vitamin B complex and was called vitamin B13, but it is now known that it is not a vitamin. The compound is manufactured in the body via a mitochondrial enzyme, dihydroorotate dehydrogenase or a cytoplasmic enzyme of pyrimidine synthesis pathway.

Similar Compounds

Methyl orotate (6153-44-2)

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5-Methylorotic acid (3993-73-5)

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705-36-2 (705-36-2)

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5-Fluoroorotic acid (703-95-7)

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89379-73-7 (89379-73-7)

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1,3-Dimethylorotic acid (4116-38-5)

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6-METHYLURACIL (626-48-2)

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4156-75-6 (4156-75-6)

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6-(Chloromethyl)uracil (18592-13-7)

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17687-24-0 (60779-49-9, 17687-24-0)

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6-isobutyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxylic acid hydrate (1609396-45-3)

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pyrimidine-4-carboxylic acid (31462-59-6)

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15043-03-5 (15043-03-5)

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5-bromo-6-methylpyrimidine-2,4-diol (15018-56-1)

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6311-73-5 (6311-73-5)

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pyrimidine-4,6-dicarboxylic acid (16490-02-1)

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6-(Trifluoromethyl)uracil (672-45-7)

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24048-74-6 (24048-74-6)

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52047-16-2 (52047-16-2)

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methyl pyrimidine-4-carboxylate (2450-08-0)

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5-chloro-6-methyluracil (16018-87-4)

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2-Methylpyrimidine-4-carboxylic acid (13627-49-1)

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Oxymethacil (7417-28-9)

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147-61-5 (147-61-5)

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2-Aminopyrimidine-4-carboxylic acid (2164-65-0)

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3,6-dimethylpyrimidine-2,4(1h,3h)-dione (19674-60-3)

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99066-77-0 (99066-77-0)

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7-oxo-7H-[1,3]thiazolo[3,2-a]pyrimidine-5-carboxylic acid hydrate (1609395-62-1)

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dimethyl pyrimidine-4,6-dicarboxylate (6345-43-3)

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6-aminopyrimidine-4-carboxylic acid (38214-46-9)

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2,6-dimethylpyrimidine-4-carboxylic acid (54198-74-2)

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1126-44-9 (1126-44-9)

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6426-84-2 (6426-84-2)

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5900-40-3 (5900-40-3)

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2-isopropyl-4-pyrimidinecarboxylic acid (1060817-57-3)

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2-amino-6-methylpyrimidine-4-carboxylic acid (6630-66-6)

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27870-38-8 (27870-38-8)

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13509-52-9 (13509-52-9)

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100707-39-9 (100707-39-9)

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5-chloro-2-methylpyrimidine-4-carboxylic acid (74840-47-4)

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methyl 6-chloropyrimidine-4-carboxylate (6627-22-1)

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2,4-Dimethyl-6-hydroxypyrimidine (6622-92-0)

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5-Nitro-6-methyluracil (16632-21-6)

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2,6-dichloropyrimidine-4-carboxylic acid (16492-28-7)

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2-Amino-4-hydroxy-6-methylpyrimidine (3977-29-5)

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3-(2-chloroethyl)-6-methylpyrimidine-2,4(1H,3H)-dione (22359-13-3)

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6-isobutyl-2-methyl-4-pyrimidinecarboxylic acid hydrochloride (1609400-12-5)

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5-Chloro-2-(methylthio)pyrimidine-4-carboxylic acid (61727-33-1)

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(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid (38580-22-2)

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2-oxo-2,3-dihydro-1H-imidazole-4-carboxylic acid (39828-47-2)

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2-Amino-6-isopropylpyrimidine-4-carboxylic acid (938458-89-0)

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50593-92-5 (50593-92-5)

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6461-30-9 (6461-30-9)

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6299-85-0 (6299-85-0)

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ethyl 2-chloro-6-methylpyrimidine-4-carboxylate (265328-14-1)

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2-Amino-6-isobutylpyrimidine-4-carboxylic acid (938458-90-3)

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6-Hydroxypicolinic acid (19621-92-2)

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1-benzyl-6-methyl-2,4(1H,3H)-pyrimidinedione (33443-58-2)

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6328-58-1 (6328-58-1)

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methylthiouracil (56-04-2)

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20901-53-5 (20901-53-5)

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5466-00-2 (5466-00-2)

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5-Bromo-1,3,6-trimethyluracil (15018-59-4)

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7-Methylimidazo[1,2-a]pyrimidin-5(8H)-one (39567-76-5)

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108-79-2 (108-79-2)

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2,4-Dihydroxypyrimidine-5-carboxylic acid (23945-44-0)

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methyl 5-amino-2,6-dichloropyrimidine-4-carboxylate (502184-51-2)

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AC1LGPPA (433253-10-2)

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5-chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid (38275-34-2)

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5,6,7,8-Tetrahydroquinazoline-2,4(1H,3H)-dione (35042-48-9)

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2-(chloromethyl)-8-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (87591-84-2)

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89284-85-5 (89284-85-5)

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135481-57-1 (135481-57-1)

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2-(chloromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (16867-35-9)

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methyl 6-amino-2,5-dichloropyrimidine-4-carboxylate (502142-81-6)

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5-Bromouracil (51-20-7)

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1,7-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-5-carboxylic acid (110181-69-6)

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35523-72-9 (35523-72-9)

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5-Formyluracil (1195-08-0)

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5-Hydroxy-1H-pyrazole-3-carboxylic acid (37832-55-6)

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CHELIDAMIC ACID (138-60-3)

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ethyl 5-formyl-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate (462095-37-0)

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5-Hydroxymethyluracil (4433-40-3)

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55878-45-0 (55878-45-0)

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1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid (7509-13-9)

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5-Carbethoxyuracil (28485-17-8)

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149771-08-4 (149771-08-4)

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2-amino-5,6,7,8-tetrahydro-4-quinazolinecarboxylic acid (51640-97-2)

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(2-methylpyrimidin-4-yl)methanol (1131605-06-5)

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50290-51-2 (50290-51-2)

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6-methyl-4-oxo-1,4-dihydro-2-pyridinecarboxylic acid (14255-41-5)

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2-(chloromethyl)-7-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (87591-79-5)

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1,8-Naphthyridine-2-carboxylic acid (215523-34-5)

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368-54-7 (368-54-7)

4 alternate names

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Orotic acid

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