Weight | 264.369 g/mol |
---|---|
Formula | C15H24N2O2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 0 |
Aromatic Rings | 0 |
Rotatable Bonds | 0 |
Oxymatrine (16837-52-8)
Score:
#321 in Neuroscience
,
#452 in Biochemistry
,
#1472 in Biology
,
#1726 in Chemistry
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- Sigma-Aldrich - Search for Oxymatrine
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- Oxymatrine protects rat brains against permanent focal ischemia and downregulates NF-B expression (Brain Research, 2009)
- Anti-tumor activities of matrine and oxymatrine: literature review (Tumor Biology, 2014)
- Anti-inflammatory mechanism of oxymatrine in dextran sulfate sodium-induced colitis of rats (World Journal of Gastroenterology, 2005)
- Oxymatrine therapy for chronic hepatitis B: A randomized double- blind and placebo-controlled multi-center trial (World Journal of Gastroenterology, 2003)
- Process optimization, characterization and evaluation in vivo of oxymatrine-phospholipid complex. (International Journal of Pharmaceutics, 2010)
- Effects of oxymatrine on proliferation and apoptosis in human hepatoma cells. (Colloids and Surfaces B: Biointerfaces, 2006)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CC2C3CCC[N+]4(C3C(CCC4)CN2C(=O)C1)[O-]
-
InChIKeyXVPBINOPNYFXID-UHFFFAOYSA-N
- Pubchem - Oxymatrine
- Wikipedia - Ammothamnine
Oxymatrine (matrine oxide, matrine N-oxide, matrine 1-oxide) is one of many quinolizidine alkaloid compounds extracted from the root of Sophora flavescens, a Chinese herb. It is very similar in structure to matrine, which has one less oxygen atom. Oxymatrine has a variety of effects in vitro and in animal models, including protection against apoptosis, tumor and fibrotic tissue development, and inflammation.
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