| Weight | 325.537 g/mol |
|---|---|
| Formula | C20H39NO2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 17 |
n-oleoylethanolamine (111-58-0)
N-OEA
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- Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues. (Chemistry and Physics of Lipids, 2006)
- N-Oleoylethanolamine Inhibits Glucosylation of Natural Ceramides in CHP-100 Neuroepithelioma Cells: Possible Implications for Apoptosis (Biochemical and Biophysical Research Communications, 1999)
- Vasorelaxation to N-oleoylethanolamine in rat isolated arteries: mechanisms of action and modulation via cyclooxygenase activity. (British Journal of Pharmacology, 2010)
- Hydrogen peroxide as a mediator of vasorelaxation evoked by N-oleoylethanolamine and anandamide in rat small mesenteric arteries. (European Journal of Pharmacology, 2012)
- Gastric bypass in morbid obese patients is associated with reduction in adipose tissue inflammation via N-oleoylethanolamide (OEA)-mediated pathways (Thrombosis and Haemostasis, 2014)
- A simple method for simultaneous determination of N-arachidonoylethanolamine, N-oleoylethanolamine, N-palmitoylethanolamine and 2-arachidonoylglycerol in human cells (Analytical and Bioanalytical Chemistry, 2015)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - N-OEA
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SMILESCCCCCCCCC=CCCCCCCCC(=O)NCCO
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InChIKeyBOWVQLFMWHZBEF-UHFFFAOYSA-N
- Pubchem - n-oleoylethanolamine
- Wikipedia - oleic monoethanolamide
Oleoylethanolamine (OEA) is an endogenous peroxisome proliferator-activated receptor alpha (PPAR-) agonist. It is a naturally occurring ethanolamide lipid that regulates feeding and body weight in vertebrates ranging from mice to pythons. OEA is the monounsaturated analogue of the endocannabinoid anandamide, but unlike anandamide it acts independently of the cannabinoid pathway, regulating PPAR- activity to stimulate lipolysis.
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n-oleoylethanolamine
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