Weight | 166.176 g/mol |
---|---|
Formula | C9H10O3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 2 |
PAEONOL (552-41-0)
2-hydroxy-4-methoxyacetophenone · peonol
Score:
#1978 in Biochemistry
,
#4175 in Biology
,
#5261 in Chemistry
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- Anti-inflammatory and analgesic effects of paeonol in carrageenan-evoked thermal hyperalgesia. (British Journal of Pharmacology, 2003)
- Paeonol attenuates neurotoxicity and ameliorates cognitive impairment induced by d-galactose in ICR mice (Journal of the Neurological Sciences, 2009)
- Development of microwave-assisted extraction followed by headspace single-drop microextraction for fast determination of paeonol in traditional Chinese medicines (Journal of Chromatography A, 2006)
- Paeonol reduced cerebral infarction involving the superoxide anion and microglia activation in ischemia-reperfusion injured rats (Journal of Ethnopharmacology, 2006)
- Paeonol inhibits anaphylactic reaction by regulating histamine and TNF- (International Immunopharmacology, 2004)
- Paeonol suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor--stimulated human umbilical vein endothelial cells by blocking p38, ERK and nuclear factor-B signaling pathways (International Immunopharmacology, 2007)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 2-hydroxy-4-methoxyacetophenone
- peonol
-
SMILESCC(=O)C1=C(C=C(C=C1)OC)O
-
InChIKeyUILPJVPSNHJFIK-UHFFFAOYSA-N
- Pubchem - PAEONOL
- Wikipedia - paeonol
Paeonol is a phenolic compound found in peonies such as Paeonia suffruticosa (moutan cortex), in Arisaema erubescens, and in Dioscorea japonica. It is a component found in some Traditional Chinese medicine remedies.
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Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
Reactant
+
Methyl hydroperoxide
(Dakin oxidation)
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