| Weight | 340.427 g/mol |
|---|---|
| Formula | C19H24N4O2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 10 |
pentamidine
Pentamidine Isethionate · Pentam · NebuPent
6823-79-6, 100-33-4, 140-64-7
Score:
#27 in Microbiology
,
#531 in Biology
,
#564 in Chemistry
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- A controlled trial of trimethoprim-sulfamethoxazole or aerosolized pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome. AIDS Clinical Trials Group Protocol 021. (The New England Journal of Medicine, 1992)
- Pentamidine: A Review (Clinical Infectious Diseases, 1985)
- Trimethoprim-Sulfamethoxazole Compared with Pentamidine for Treatment of Pneumocystis carinii Pneumonia in the Acquired Immunodeficiency Syndrome: A Prospective, Noncrossover Study (Annals of Internal Medicine, 1988)
- Trimethoprim-Sulfamethoxazole or Pentamidine for Pneumocystis carinii Pneumonia in the Acquired Immunodeficiency Syndrome: A Prospective Randomized Trial (Annals of Internal Medicine, 1986)
- Aerosolized pentamidine for prophylaxis against Pneumocystis carinii pneumonia. The San Francisco community prophylaxis trial. (The New England Journal of Medicine, 1990)
- Pentamidine-Induced Long QT Syndrome and Block of hERG Trafficking (Journal of Pharmacology and Experimental Therapeutics, 2004)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Pentamidine Isethionate
- Pentam
- NebuPent
- Diamidine
- Pentacarinat
- Lomidine
- Pentamidin
- Pentamidine Mesylate
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SMILESC1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)N
-
InChIKeyXDRYMKDFEDOLFX-UHFFFAOYSA-N
- Pubchem - pentamidine
- Wikipedia - pentamidine
Pentamidine is an antimicrobial medication used to treat African trypanosomiasis, leishmaniasis, babesiosis, and to prevent and treat pneumocystis pneumonia (PCP) in people with poor immune function. In African trypanosomiasis it is used for early disease before central nervous system involvement, as a second line option to suramin. It is an option for both visceral leishmaniasis and cutaneous leishmaniasis.
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Areas of Application
Safety
Trends
Alternate Names
Estimated Properties
| Density | 1.29 g/cm3 | EPA T.E.S.T. |
|---|---|---|
| Flash Point | 253.75 C | EPA T.E.S.T. |
External Links
Synthesis
CID 217125
+
Reactant
(Williamson ether)
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pentamidine
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