Weight | 285.431 g/mol |
---|---|
Formula | C19H27NO |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 2 |
pentazocine
Talwin · Pentazocine Hydrochloride · Pentazocine Lactate
7488-49-5, 359-83-1, 21820-34-8, 55643-30-6
Score:
#309 in Neuroscience
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#1379 in Biology
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#1613 in Chemistry
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- Gender difference in analgesic response to the kappa-opioid pentazocine (Neuroscience Letters, 1996)
- Characterization of the binding of [3H](+)-pentazocine to recognition sites in guinea pig brain (European Journal of Pharmacology, 1992)
- Synthesis and evaluation of optically pure [3H]-(+)-pentazocine, a highly potent and selective radioligand for receptors (FEBS Letters, 1989)
- Effects of short- and long-term administration of pentazocine in man. (Clinical Pharmacology & Therapeutics, 1970)
- [3H]1,3-di(2-tolyl)guanidine and [3H](+)pentazocine binding sites in the rat brain: Autoradiographic visualization of the putative sigma1 and sigma2 receptor subtypes (Neuroscience, 1997)
- Design, Development, and Biopharmaceutical Properties of Buccoadhesive Compacts of Pentazocine (Drug Development and Industrial Pharmacy, 1999)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Talwin
- Pentazocine Hydrochloride
- Pentazocine Lactate
- Fortral
- Lexir
-
SMILESCC1C2CC3=C(C1(CCN2CC=C(C)C)C)C=C(C=C3)O
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InChIKeyVOKSWYLNZZRQPF-UHFFFAOYSA-N
- Pubchem - pentazocine
- Wikipedia - (-)-pentazocine
Pentazocine, sold under the brand name Talwin among others, is a painkiller used to treat moderate to severe pain. It is believed to work by activating (agonizing) -opioid receptors (KOR) and blocking (antagonizing) -opioid receptors (MOR). As such it is called an opioid as it delivers its effects on pain by interacting with the opioid receptors.
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