| Weight | 308.381 g/mol |
|---|---|
| Formula | C19H20N2O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
Phenylbutazone (50-33-9)
Butazolidin · Butadione · Butapyrazole
Score:
#455 in Biology
,
#476 in Chemistry
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- Warfarin STEREOCHEMICAL ASPECTS OF ITS METABOLISM AND THE INTERACTION WITH PHENYLBUTAZONE (Journal of Clinical Investigation, 1974)
- THE PHYSIOLOGICAL DISPOSITION OF PHENYLBUTAZONE (BUTAZOLIDIN) IN MAN AND A METHOD FOR ITS ESTIMATION IN BIOLOGICAL MATERIAL (Journal of Pharmacology and Experimental Therapeutics, 1953)
- Comparison of adverse effects of phenylbutazone, flunixin meglumine, and ketoprofen in horses (Javma-journal of The American Veterinary Medical Association, 1993)
- Potentiation of anticoagulant effect of warfarin by phenylbutazone. (The New England Journal of Medicine, 1967)
- Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone, quinidine, quinine, and sulfinpyrazone) "probes" for human udp-glucuronosyltransferases. (Drug Metabolism and Disposition, 2005)
- Effect of activated charcoal on absorption and elimination of phenobarbitone, carbamazepine and phenylbutazone in man (European Journal of Clinical Pharmacology, 1980)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Butazolidin
- Butadione
- Butapyrazole
- Diphenylbutazone
- Butapirazol
- Fenilbutazon
- Butadion
- Butacote
-
SMILESCCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3
-
InChIKeyVYMDGNCVAMGZFE-UHFFFAOYSA-N
- Pubchem - Phenylbutazone
- Wikipedia - phenylbutazone
Phenylbutazone, often referred to as "bute," is a nonsteroidal anti-inflammatory drug (NSAID) for the short-term treatment of pain and fever in animals. In the United States and United Kingdom it is no longer approved for human use (except for ankylosing spondylitis, because no other treatment is available), as it can cause severe adverse effects such as suppression of white blood cell production and aplastic anemia. This drug was implicated in the 2013 meat adulteration scandal.
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Estimated Properties
| Density | 1.17 g/cm3 | EPA T.E.S.T. |
|---|---|---|
| Flash Point | 186.28 C | EPA T.E.S.T. |
| Water Solubility | 41.23 mg/L | EPA T.E.S.T. |
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