| Weight | 409.41 g/mol |
|---|---|
| Formula | C18H10F3NO3S2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
CFTRinh-172 (307510-92-5)
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- Evidence for direct CFTR inhibition by CFTRinh-172 based on Arg347 mutagenesis (Biochemical Journal, 2008)
- Cystic Fibrosis Transmembrane Regulator Inhibitors CFTRinh-172 and GlyH-101 Target Mitochondrial Functions, Independently of Chloride Channel Inhibition (Journal of Pharmacology and Experimental Therapeutics, 2010)
- Divergent CFTR orthologs respond differently to the channel inhibitors CFTRinh-172, glibenclamide, and GlyH-101. (American Journal of Physiology-cell Physiology, 2012)
- Revisiting CFTR inhibition: a comparative study of CFTRinh172 and GlyH101 inhibitors (British Journal of Pharmacology, 2014)
- CFTR channel pharmacology: insight from a flock of clones. Focus on Divergent CFTR orthologs respond differently to the channel inhibitors CFTRinh-172, glibenclamide, and GlyH-101 (American Journal of Physiology-cell Physiology, 2012)
- On the Mechanism of CFTR Inhibition by CFTRinh-172 (Biophysical Journal, 2009)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=CC(=CC(=C1)N2C(=O)C(=CC3=CC=C(C=C3)C(=O)O)SC2=S)C(F)(F)F
-
InChIKeyJIMHYXZZCWVCMI-UHFFFAOYSA-N
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