| Weight | 600.478 g/mol |
|---|---|
| Formula | C26H25F9N2O4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
Torcetrapib (262352-17-0)
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- Sigma-Aldrich - Torcetrapib110.50 - 401.50 USD
- Fisher Scientific - Search for Torcetrapib
- TCI - Search for Torcetrapib
- Effects of Torcetrapib in Patients at High Risk for Coronary Events (The New England Journal of Medicine, 2007)
- Effect of Torcetrapib on the Progression of Coronary Atherosclerosis (The New England Journal of Medicine, 2007)
- Effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia (The New England Journal of Medicine, 2007)
- Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double-blind trial (The Lancet, 2007)
- Raising High-Density Lipoprotein in Humans Through Inhibition of Cholesteryl Ester Transfer Protein An Initial Multidose Study of Torcetrapib (Arteriosclerosis, Thrombosis, and Vascular Biology, 2004)
- The Failure of Torcetrapib Was it the Molecule or the Mechanism (Arteriosclerosis, Thrombosis, and Vascular Biology, 2006)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC1CC(C2=C(N1C(=O)OCC)C=CC(=C2)C(F)(F)F)N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C(=O)OC
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InChIKeyCMSGWTNRGKRWGS-UHFFFAOYSA-N
- Pubchem - Torcetrapib
- Wikipedia - torcetrapib
Torcetrapib (CP-529,414, Pfizer) was a drug being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease. Its development was halted in 2006 when phase III studies showed excessive all-cause mortality in the treatment group receiving a combination of atorvastatin (Lipitor) and torcetrapib.
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Torcetrapib
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