| Weight | 224.267 g/mol |
|---|---|
| Formula | C13H12N4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 1 |
PhIP (105650-23-5)
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
Score:
#26 in Biochemistry
,
#170 in Biology
,
#175 in Chemistry
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- A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP) (Carcinogenesis, 1991)
- The prostate : A target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods (Cancer Research, 1997)
- The isolation and identification of a new mutagen from fried ground beef: 2-amino-l-methyl-6-phenylimidazo[4, 5-b]pyridine (PhIP) (Carcinogenesis, 1986)
- High Concentrations of the Carcinogen 2-Amino-1-methyl-6-phenylimidazo (4,5-b)pyridine (PhIP) Occur in Chicken but Are Dependent on the Cooking Method' (Cancer Research, 1995)
- Human Breast Cancer Resistance Protein: Interactions with Steroid Drugs, Hormones, the Dietary Carcinogen 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and Transport of Cimetidine (Journal of Pharmacology and Experimental Therapeutics, 2004)
- The Breast Cancer Resistance Protein (Bcrp1/Abcg2) Restricts Exposure to the Dietary Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (Cancer Research, 2003)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
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SMILESCN1C2=C(N=CC(=C2)C3=CC=CC=C3)N=C1N
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InChIKeyUQVKZNNCIHJZLS-UHFFFAOYSA-N
- Pubchem - PhIP
- Wikipedia - 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) is one of the most abundant heterocyclic amines (HCAs) in cooked meat. PhIP is formed at high temperatures from the reaction between creatine or creatinine (found in muscle meats), amino acids, and sugar. PhIP formation increases with the temperature and duration of cooking and also depends on the method of cooking and the variety of meat being cooked.
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Alternate Names
Estimated Properties
| Boiling Point | 364.88 C | EPA T.E.S.T. |
|---|---|---|
| Density | 1.4 g/cm3 | EPA T.E.S.T. |
| Flash Point | 250.28 C | EPA T.E.S.T. |
| Water Solubility | 164.85 mg/L | EPA T.E.S.T. |
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