| Weight | 362.407 g/mol |
|---|---|
| Formula | C17H18N2O5S |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
piretanide (55837-27-9)
HOE 118 · 4-phenoxy-3-pyrrolidin-1-yl-5-sulfamoylbenzoic acid
"What do you need help with?"
LabBot
- Sigma-Aldrich - Search for piretanide
- Fisher Scientific - Search for piretanide
- TCI - Search for piretanide
- Inhibition of active chloride transport by piretanide. (Nature, 1978)
- Buoyancy and Drug Release Patterns of Floating Minitablets Containing Piretanide and Atenolol as Model Drugs (Pharmaceutical Development and Technology, 1998)
- K+-induced swelling of vestibular dark cells is dependent on Na+ and Cl and inhibited by piretanide (Pflgers Archiv: European Journal of Physiology, 1990)
- Effects of piretanide, bumetanide and frusemide on electrolyte and urate excretion in normal subjects. (British Journal of Clinical Pharmacology, 1978)
- Kinetic and dynamic comparison of piretanide and furosemide. (Clinical Pharmacology & Therapeutics, 1978)
- Electrochemical determination of the loop diuretics piretanide and furosemide in pharmaceutical formulations and urine (Analytica Chimica Acta, 1995)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - HOE 118
- 4-phenoxy-3-pyrrolidin-1-yl-5-sulfamoylbenzoic acid
-
SMILESC1CCN(C1)C2=C(C(=CC(=C2)C(=O)O)S(=O)(=O)N)OC3=CC=CC=C3
-
InChIKeyUJEWTUDSLQGTOA-UHFFFAOYSA-N
- Pubchem - piretanide
- Wikipedia - piretanide
Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups. Studies of piretanide in rats and dogs in comparison with other high-ceiling diuretics such as furosemide and bumetanide found a more suitable dose/response rate (regression line) and a more favourable sodium/potassium excretion ratio. These findings led eventually to clinical studies in man and finally to the introduction as a saluretic and antihypertensive medication in Germany, France, Italy and other countries.
Suppliers
Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
External Links
Similar Compounds
Nordiazepam
(1088-11-5)
3 alternate names
3 suppliers
succinylsulfathiazole
(116-43-8)
3 alternate names
3 suppliers
N-Fluorobenzenesulfonimide
(133745-75-2)
3 alternate names
3 suppliers
Fenpyroximate
(111812-58-9)
3 alternate names
3 suppliers
sulfaquinoxaline
(59-40-5)
3 alternate names
3 suppliers
FLURIDONE
(59756-60-4)
3 alternate names
3 suppliers
56803-37-3
(83242-23-3, 56803-37-3)
3 alternate names
3 suppliers
o-Isopropylphenyl diphenyl phosphate
(93925-53-2, 64532-94-1)
3 alternate names
3 suppliers
Eletriptan hydrobromide
(177834-92-3)
3 alternate names
3 suppliers
Centralite
(85-98-3)
3 alternate names
3 suppliers
medazepam
(2898-12-6)
3 alternate names
3 suppliers
Trifluperidol
(749-13-3)
3 alternate names
3 suppliers
Mefenacet
(73250-68-7)
3 alternate names
3 safety hazards
3 suppliers
Enrofloxacin
(93106-60-6)
3 alternate names
3 suppliers
(S)-atropinium
(101-31-5)
3 alternate names
1 safety hazard
3 suppliers
Diphyl
(8004-13-5)
3 alternate names
3 suppliers
2-Diphenylmethylpiperidine
(519-74-4)
3 alternate names
3 suppliers
Diethylene glycol dibenzoate
(120-55-8)
3 alternate names
3 suppliers
pridinol
(511-45-5)
3 alternate names
3 suppliers
Ajmalicine
(483-04-5)
3 alternate names
3 suppliers
diclofenac epolamine
(119623-66-4)
3 alternate names
3 suppliers
ERIODICTYOL
(552-58-9, 4049-38-1)
3 alternate names
3 suppliers
halazone
(80-13-7)
3 alternate names
3 suppliers
BENALAXYL
(71626-11-4)
3 alternate names
2 safety hazards
3 suppliers
fenvalerate
(51630-58-1, 66267-77-4, 67614-33-9, 67614-32-8)
3 alternate names
4 safety hazards
3 suppliers
resmethrin
(35764-59-1, 10453-86-8, 3690-58-2, 28434-01-7)
3 alternate names
4 safety hazards
3 suppliers
Diphacinone
(82271-36-1, 82-66-6)
3 alternate names
4 safety hazards
3 suppliers
Asenapine
(65576-45-6)
3 alternate names
3 suppliers
Asenapine
(65576-45-6)
3 alternate names
3 suppliers
DICYCLOHEXYL PHTHALATE
(84-61-7)
3 alternate names
1 safety hazard
3 suppliers
Asenapine
(65576-45-6)
3 alternate names
3 suppliers
Asenapine
(65576-45-6)
3 alternate names
3 suppliers
BENSULIDE
(741-58-2)
3 alternate names
2 safety hazards
3 suppliers
CHLORSULFURON
(112143-77-8, 64902-72-3)
3 alternate names
2 safety hazards
3 suppliers
Fenazaquin
(120928-09-8)
3 alternate names
3 safety hazards
3 suppliers
DICUMYL PEROXIDE
(80-43-3)
3 alternate names
4 safety hazards
3 suppliers
Trifenmorph
(1420-06-0)
3 alternate names
2 safety hazards
3 suppliers
1,8-Naphthalic anhydride
(81-84-5)
3 alternate names
3 suppliers
Pipradrol
(467-60-7)
3 alternate names
3 suppliers
phenethicillin
(132-93-4, 147-55-7)
3 alternate names
3 suppliers
CAS Directory
