| Weight | 185.226 g/mol |
|---|---|
| Formula | C12H11NO |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 1 |
PIRFENIDONE (53179-13-8)
Score:
#336 in Biochemistry
,
#1244 in Biology
,
#1431 in Chemistry
"What do you need help with?"
LabBot
- A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis. (The New England Journal of Medicine, 2014)
- Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. (The Lancet, 2011)
- Double-blind, Placebo-controlled Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis (American Journal of Respiratory and Critical Care Medicine, 2005)
- Pirfenidone in idiopathic pulmonary fibrosis (European Respiratory Journal, 2010)
- Treatment of Idiopathic Pulmonary Fibrosis with a New Antifibrotic Agent, Pirfenidone Results of a Prospective, Open-label Phase II Study (American Journal of Respiratory and Critical Care Medicine, 1999)
- Effects of Pirfenidone on Transforming Growth Factor- Gene Expression at the Transcriptional Level in Bleomycin Hamster Model of Lung Fibrosis (Journal of Pharmacology and Experimental Therapeutics, 1999)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=CN(C(=O)C=C1)C2=CC=CC=C2
-
InChIKeyISWRGOKTTBVCFA-UHFFFAOYSA-N
- Pubchem - PIRFENIDONE
- Wikipedia - pirfenidone
Pirfenidone is a medication used for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. It was developed by several companies worldwide, including the original patent holder, Marnac, InterMune Inc.
Suppliers
Most-cited Publications
Areas of Application
Safety
Alternate Names
External Links
Similar Compounds
4948-15-6
(4948-15-6)
1 alternate name
3 suppliers
4-methyl-1-phenylquinolin-2(1h)-one
(2540-30-9)
1 alternate name
3 suppliers
C.I. Pigment Red 123
(24108-89-2)
1 alternate name
3 suppliers
1-(4-bromophenyl)-1H-pyrrole-3-carbaldehyde
(477850-19-4)
1 alternate name
3 suppliers
2-Hydroxy-5-methylpyridine
(1003-68-5, 91914-06-6, 1192-99-0)
1 alternate name
3 suppliers
6275-84-9
(6275-84-9)
1 alternate name
3 suppliers
4-(1H-PYRROL-1-YL)BENZYLAMINE
(465514-27-6)
1 alternate name
3 suppliers
4-(1H-Pyrrol-1-yl)benzonitrile
(23351-07-7)
1 alternate name
3 suppliers
4-(1H-Pyrrol-1-yl)benzaldehyde
(23351-05-5)
1 alternate name
3 suppliers
75837-81-9
(75837-81-9)
1 alternate name
3 suppliers
1-phenyl-1,3-dihydro-2H-imidazol-2-one
(53995-06-5)
1 alternate name
3 suppliers
2-(1H-pyrrol-1-yl)benzonitrile
(33265-71-3)
1 alternate name
3 suppliers
5,6-dimethylpyridin-2-ol
(27992-31-0)
1 alternate name
3 suppliers
[4-(1H-Pyrrol-1-yl)phenyl]methanol
(143426-51-1)
1 alternate name
3 suppliers
33252-63-0
(33252-63-0)
1 alternate name
3 suppliers
3-METHYL-4-(1H-PYRROL-1-YL)PHENOL
(137352-74-0)
1 alternate name
3 suppliers
2,5-dimethyl-1-(2-naphthyl)-1H-pyrrole-3-carbaldehyde
(347332-17-6)
1 alternate name
3 suppliers
5-(1H-pyrrol-1-yl)nicotinic acid
(690632-31-6)
1 alternate name
3 suppliers
1-Phenyl-1H-benzo[d]imidazol-2(3H)-one
(14813-85-5)
1 alternate name
3 suppliers
1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde
(119673-50-6)
1 alternate name
3 suppliers
241488-81-3
(241488-81-3)
1 alternate name
3 suppliers
22106-37-2
(22106-37-2)
1 alternate name
3 suppliers
1-(4-Bromophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde
(347331-78-6)
1 alternate name
3 suppliers
4-(1H-pyrrol-1-yl)benzohydrazide
(112575-84-5)
1 alternate name
3 suppliers
4-(4-oxoquinazolin-3(4h)-yl)benzoic acid
(94242-54-3)
1 alternate name
3 suppliers
603-23-6
(603-23-6)
1 alternate name
3 suppliers
2,5-DIMETHYL-1-(P-TOLYL)-PYRROLE
(32411-27-1)
1 alternate name
3 suppliers
2-Methyl-3-(1H-pyrrol-1-yl)aniline
(137352-75-1)
1 alternate name
3 suppliers
1-Phenylpyrrole
(635-90-5)
1 alternate name
3 suppliers
2-Methyl-5-pyrrol-1-yl-phenylamine
(137352-77-3)
1 alternate name
3 suppliers
52034-38-5
(52034-38-5)
1 alternate name
3 suppliers
methyl 6-hydroxynicotinate
(66171-50-4)
1 alternate name
3 suppliers
1-(3-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde
(428497-01-2)
1 alternate name
3 suppliers
1-Phenyl-1H-indole
(31096-91-0)
1 alternate name
3 suppliers
2,5-Dimethyl-1-phenylpyrrole
(83-24-9)
1 alternate name
3 suppliers
2,5-dimethyl-1-pyridin-3-yl-1H-pyrrole-3-carbaldehyde
(35711-47-8)
1 alternate name
3 suppliers
1-[4-(dimethylamino)phenyl]-2,5-dimethyl-1H-pyrrole-3-carbaldehyde
(32570-93-7)
1 alternate name
3 suppliers
1-(4-methoxyphenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde
(347331-30-0)
1 alternate name
3 suppliers
1-(3-bromophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde
(812642-64-1)
1 alternate name
3 suppliers
22048-71-1
(22048-71-1)
1 alternate name
3 suppliers
methyl 4-(3-formyl-2,5-dimethyl-1H-pyrrol-1-yl)benzoate
(347332-01-8)
1 alternate name
3 suppliers
9-Phenylcarbazole
(1150-62-5)
1 alternate name
3 suppliers
3-methylpyridin-2-ol
(1003-56-1)
1 alternate name
3 suppliers
27440-42-2
(27440-42-2)
1 alternate name
3 suppliers
[2-oxo-5-(trifluoromethyl)-1(2H)-pyridinyl]acetic acid
(308294-33-9)
1 alternate name
3 suppliers
3-(1H-pyrrol-1-yl)benzoic acid
(61471-45-2)
1 alternate name
3 suppliers
2-(2-methyl-1-phenyl-1H-indol-3-yl)ethanamine
(28856-30-6)
1 alternate name
3 suppliers
2-(2-Methyl-1-Phenyl-1H-Indol-3-Yl)-Ethylamine Hydrochloride
(692739-71-2)
1 alternate name
3 suppliers
2,5-dimethyl-1-phenyl-1h-pyrrole-3-carboxylic acid
(3807-56-5)
1 alternate name
3 suppliers
ethyl 4-(3-formyl-2,5-dimethyl-1H-pyrrol-1-yl)benzoate
(52034-37-4)
1 alternate name
3 suppliers
207233-99-6
(207233-99-6)
1 alternate name
3 suppliers
98105-79-4
(98105-79-4)
1 alternate name
3 suppliers
1-(4-Nitrophenyl)-1H-pyrrole
(4533-42-0)
1 alternate name
3 suppliers
1-(4-Chlorophenyl)-1H-pyrrole
(5044-38-2)
1 alternate name
3 suppliers
328028-87-1
(328028-87-1)
1 alternate name
3 suppliers
1-(4-fluorophenyl)-1H-pyrrole
(81329-31-9)
1 alternate name
3 suppliers
15898-26-7
(15898-26-7)
1 alternate name
3 suppliers
4-(2-methyl-4-oxoquinazolin-3(4H)-yl)benzoic acid
(4005-05-4)
1 alternate name
3 suppliers
23965-11-9
(23965-11-9)
1 alternate name
3 suppliers
1-(2-bromophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde
(662154-13-4)
1 alternate name
3 suppliers
60176-19-4
(60176-19-4)
1 alternate name
3 suppliers
3-Hydroxy-1-phenylpyridinium chloride
(15941-41-0)
1 alternate name
3 suppliers
1-(2-chlorophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde
(119673-49-3)
1 alternate name
3 suppliers
409353-42-0
(409353-42-0)
1 alternate name
3 suppliers
3-Methyl-4-pyrrol-1-yl-benzoic acid
(593272-74-3)
1 alternate name
3 suppliers
1-(4-iodophenyl)-2,5-dimethyl-1H-pyrrole
(288608-09-3)
1 alternate name
3 suppliers
2-hydrazino-3-phenylquinazolin-4(3H)-one
(731-52-2)
1 alternate name
3 suppliers
2-(1H-pyrrol-1-yl)benzohydrazide
(31739-63-6)
1 alternate name
3 suppliers
3-(2,5-dimethyl-1H-pyrrol-1-yl)aniline
(247225-33-8)
1 alternate name
3 suppliers
26165-67-3
(26165-67-3)
1 alternate name
3 suppliers
4-(1H-Pyrrol-1-yl)phenol
(23351-09-9)
1 alternate name
3 suppliers
1-(2-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde
(153881-54-0)
1 alternate name
3 suppliers
1-phenyl-1H-pyrrole-2-carbaldehyde
(30186-39-1)
1 alternate name
3 suppliers
[4-(3-formyl-2,5-dimethyl-1H-pyrrol-1-yl)phenoxy]acetic acid
(662154-28-1)
1 alternate name
3 suppliers
4-Methyl-3-pyrrol-1-yl-benzoic acid
(593272-75-4)
1 alternate name
3 suppliers
18741-24-7
(18741-24-7)
1 alternate name
3 suppliers
26165-66-2
(26165-66-2)
1 alternate name
3 suppliers
2-(1H-pyrrol-1-yl)benzoic acid
(10333-68-3)
1 alternate name
3 suppliers
1-(4-bromophenyl)-1H-pyrrole
(5044-39-3)
1 alternate name
3 suppliers
1-(3-nitrophenyl)-1H-pyrrole
(4310-42-3)
1 alternate name
3 suppliers
1-(3-methylphenyl)-1H-pyrrole-2-carbaldehyde
(86454-35-5)
1 alternate name
3 suppliers
1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid
(3719-45-7)
1 alternate name
3 suppliers
methyl 3-(3-formyl-2,5-dimethyl-1H-pyrrol-1-yl)benzoate
(428473-45-4)
1 alternate name
3 suppliers
26165-63-9
(26165-63-9)
1 alternate name
3 suppliers
BASIC RED 2
(477-73-6)
1 alternate name
3 suppliers
5-methyl-2-(1H-pyrrol-1-yl)aniline
(59194-21-7)
1 alternate name
3 suppliers
2,5-dimethyl-1-(4-nitrophenyl)-1H-pyrrole
(5044-22-4)
1 alternate name
3 suppliers
1-(4-methoxyphenyl)-2,5-dimethylpyrrole
(5044-27-9)
1 alternate name
3 suppliers
5159-70-6
(5159-70-6)
1 alternate name
3 suppliers
afloqualone
(56287-74-2)
1 alternate name
3 suppliers
444077-56-9
(444077-56-9)
1 alternate name
3 suppliers
4-(3-acetyl-2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid
(870540-39-9)
1 alternate name
3 suppliers
175205-51-3
(175205-51-3)
1 alternate name
3 suppliers
NS-1619
(153587-01-0)
1 alternate name
3 suppliers
1028-39-3
(1028-39-3)
1 alternate name
3 suppliers
6375-89-9
(6375-89-9)
1 alternate name
3 suppliers
1547-15-5
(1547-15-5)
1 alternate name
3 suppliers
1-(2-methylphenyl)-1H-pyrrole-2-carbaldehyde
(35524-41-5)
1 alternate name
3 suppliers
2-Methyl-3-pyrrol-1-yl-benzoic acid
(83140-96-9)
1 alternate name
3 suppliers
PIRFENIDONE
CAS Directory
