Weight | 1085.156 g/mol |
---|---|
Formula | C52H76O24 |
Hydrogen Acceptors | 24 |
Hydrogen Donors | 11 |
Aromatic Rings | 2 |
Rotatable Bonds | 15 |
plicamycin (18378-89-7)
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- Preliminary Observations on the Therapy of the Myeloid Blast Phase of Chronic Granulocytic Leukemia with Plicamycin and Hydroxyurea (The New England Journal of Medicine, 1986)
- Original article: Plicamycin and pamidronate in symptomatic tumor-related hypercalcemia: A prospective randomized crossover trial (Annals of Oncology, 1992)
- A pilot study of alpha-interferon and plicamycin for accelerated phase of chronic myeloid leukemia (Leukemia Research, 1997)
- LongTerm FollowUp of Stage III Testicular Carcinoma Treated With Mithramycin (Plicamycin) (Medical and Pediatric Oncology, 1995)
- Dramatic response to plicamycin in a patient with severe Paget's disease refractory to calcitonin and pamidronate (Seminars in Arthritis and Rheumatism, 1994)
- Determination of plicamycin in plasma by radioimmunoassay. (Therapeutic Drug Monitoring, 1992)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1C(C(CC(O1)OC2CC(OC(C2O)C)OC3=CC4=CC5=C(C(=O)C(C(C5)C(C(=O)C(C(C)O)O)OC)OC6CC(C(C(O6)C)O)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)O)(C)O)C(=C4C(=C3C)O)O)O)O
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- Pubchem - plicamycin
- Wikipedia - Plicamycin
Plicamycin (INN, also known as mithramycin; trade name Mithracin) is an antineoplastic antibiotic produced by Streptomyces plicatus. It is an RNA synthesis inhibitor. The manufacturer discontinued production in 2000.
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