Weight | 877.045 g/mol |
---|---|
Formula | C47H64N4O12 |
Hydrogen Acceptors | 15 |
Hydrogen Donors | 6 |
Aromatic Rings | 1 |
Rotatable Bonds | 5 |
RIFAPENTINE (61379-65-5)
Score:
#379 in Microbiology
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#2962 in Biology
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#3704 in Chemistry
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- Three months of rifapentine and isoniazid for latent tuberculosis infection (The New England Journal of Medicine, 2011)
- Rifapentine and isoniazid once a week versus rifampicin and isoniazid twice a week for treatment of drug-susceptible pulmonary tuberculosis in HIV-negative patients: A randomised clinical trial (The Lancet, 2002)
- Acquired rifamycin monoresistance in patients with HIV-related tuberculosis treated with once-weekly rifapentine and isoniazid (The Lancet, 1999)
- Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model (PLOS Medicine, 2007)
- High-Dose Rifapentine with Moxifloxacin for Pulmonary Tuberculosis (The New England Journal of Medicine, 2014)
- Primary human hepatocytes as a tool for the evaluation of structureactivity relationship in cytochrome P450 induction potential of xenobiotics: evaluation of rifampin, rifapentine and rifabutin (Chemico-Biological Interactions, 1997)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1C=CC=C(C(=O)NC2=C(C3=C(C(=C4C(=C3C(=O)C2=CNN5CCN(CC5)C6CCCC6)C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C
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InChIKeyRISDZDVHYCURHD-UHFFFAOYSA-N
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