| Weight | 293.407 g/mol |
|---|---|
| Formula | C17H27NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 9 |
pramoxine (140-65-8)
Prax · pramoxine hydrochloride · Tronothane
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- Cloning and Characterization of PRAX-1 A NEW PROTEIN THAT SPECIFICALLY INTERACTS WITH THE PERIPHERAL BENZODIAZEPINE RECEPTOR (Journal of Biological Chemistry, 1999)
- A pramoxine-based anti-itch lotion is more effective than a control lotion for the treatment of uremic pruritus in adult hemodialysis patients (Journal of Dermatological Treatment, 2009)
- Effect of topical pramoxine on experimentally induced pruritus in humans (Journal of The American Academy of Dermatology, 1997)
- An evaluation of the moisturizing and anti-itch effects of a lactic acid and pramoxine hydrochloride cream. (Cutis, 2004)
- Expression Profile and Up-Regulation of Prax-1 mRNA by Antidepressant Treatment in the Rat Brain (Molecular Pharmacology, 2002)
- Topical Pramoxine and Hydrocortisone Foam versus Placebo in Relief of Post Partum Episiotomy Symptoms and Wound Healing (Scottish Medical Journal, 1984)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Prax
- pramoxine hydrochloride
- Tronothane
- proctoFoam
- Tronolane
- Ascher brand of pramoxine hydrochloride
- Isdin brand of pramoxine hydrochloride
- Abbott brand of pramoxine hydrochloride
- PrameGel
- 4-(3-(4-butoxyphenoxy)propyl)morpholine
- GenDerm brand of pramoxine hydrochloride
- Fleet Pain Relief
- pramocaine hydrochloride
- Seid brand of pramoxine hydrochloride
- Ferndale brand of pramoxine hydrochloride
- Balsabit
- pramocaine
- Ross brand of pramoxine hydrochloride
- Pramox
- 4-(3-(p-butoxyphenoxy)propyl)morpholine
- Schwarz brand of pramoxine hydrochloride
- Medicis brand of pramoxine hydrochloride
- Fleet brand of pramoxine hydrochloride
- Itch-X
-
SMILESCCCCOC1=CC=C(C=C1)OCCCN2CCOCC2
-
InChIKeyDQKXQSGTHWVTAD-UHFFFAOYSA-N
- Pubchem - pramoxine
- Wikipedia - pramoxine
Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953 and used as an antipruritic. During research and development, pramocaine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent. Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in humans.
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