Weight | 256.777 g/mol |
---|---|
Formula | C13H21ClN2O |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 5 |
Prilocaine hydrochloride (1786-81-8)
Prilocaine · Citanest · Propitocaine
Score:
#904 in Biochemistry
,
#1053 in Physics
,
#2402 in Biology
,
#2984 in Chemistry
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- A Comparison of the Hydrochloride and Carbon Dioxide Salts of Lidocaine and Prilocaine in Epidural Analgesia (Acta Anaesthesiologica Scandinavica, 1965)
- Efficacy and Safety of LidocainePrilocaine Cream for Pain during Circumcision (The New England Journal of Medicine, 1997)
- A Systematic Review of Lidocaine-Prilocaine Cream (EMLA) in the Treatment of Acute Pain in Neonates (Pediatrics, 1998)
- Age-Related Response to Lidocaine-Prilocaine (EMLA) Emulsion and Effect of Music Distraction on the Pain of Intravenous Cannulation (Pediatrics, 1994)
- DOUBLE-BLIND EVALUATION OF A LIGNOCAINE-PRILOCAINE CREAM (EMLA) IN CHILDREN Effect on the Pain Associated with Venous Cannulation (BJA: British Journal of Anaesthesia, 1986)
- FACTORS AFFECTING PLASMA LEVELS OF LIGNOCAINE AND PRILOCAINE (BJA: British Journal of Anaesthesia, 1972)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Prilocaine
- Citanest
- Propitocaine
- Xylonest
- Citanest Octapressin
-
SMILESCCCNC(C)C(=O)NC1=CC=CC=C1C.Cl
-
InChIKeyBJPJNTKRKALCPP-UHFFFAOYSA-N
- Pubchem - Prilocaine hydrochloride
- Wikipedia - prilocaine hydrochloride
Prilocaine () is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a topical preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia.
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Synthesis
Reactant
+
1-CHLOROPROPANE
(Alkylation of primary amines)
Reactant
+
o-Toluidine
(Schotten-Baumann amide from acid)
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