Weight | 271.792 g/mol |
---|---|
Formula | C13H22ClN3O |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 6 |
procainamide hydrochloride (614-39-1)
Procainamide · Pronestyl · Procaine Amide
Score:
#1092 in Biochemistry
,
#2813 in Biology
,
#3522 in Chemistry
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- Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity. (Journal of Immunology, 1988)
- Effect of Acetylator Phenotype on the Rate at Which Procainamide Induces Antinuclear Antibodies and the Lupus Syndrome (The New England Journal of Medicine, 1978)
- Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice. (Journal of Clinical Investigation, 1993)
- Procainamide Dosage Schedules, Plasma Concentrations, and Clinical Effects (JAMA, 1971)
- Effect of Verapamil and Procainamide on Atrial FibrillationInduced Electrical Remodeling in Humans (Circulation, 1997)
- Conversion efficacy and safety of intravenous ibutilide compared with intravenous procainamide in patients with atrial flutter or fibrillation (Journal of the American College of Cardiology, 1998)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Procainamide
- Pronestyl
- Procaine Amide
- Procan
- Procan SR
- Procanbid
- Rhythmin
- Procamide
- Novocainamide
- Biocoryl
- Apo-Procainamide
- Novocamid
-
SMILESCCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl
-
InChIKeyABTXGJFUQRCPNH-UHFFFAOYSA-N
- Pubchem - procainamide hydrochloride
- Wikipedia - procainamide hydrochloride
Procainamide is a medication of the antiarrhythmic class used for the treatment of cardiac arrhythmias. It is classified by the Vaughan Williams classification system as class Ia; thus it is a Na+ channel blocker of cardiomyocytes. In addition to blocking the INa current, it inhibits the IKr rectifier K+ current.
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