Weight | 401.463 g/mol |
---|---|
Formula | C21H27N3O5 |
Hydrogen Acceptors | 6 |
Hydrogen Donors | 2 |
Aromatic Rings | 2 |
Rotatable Bonds | 9 |
PYRILAMINE MALEATE (59-33-6)
Pyrilamine · Mepyramine · Anthisan
Score:
#715 in Neuroscience
,
#1292 in Biochemistry
,
#3167 in Biology
,
#3964 in Chemistry
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- HETEROGENEITY OF HISTAMINE HiRECEPTORS: SPECIES VARIATIONS IN [3H]MEPYRAMINE BINDING OF BRAIN MEMBRANES (Journal of Neurochemistry, 1979)
- Cardiac Electrophysiological Actions of the Histamine H1-Receptor Antagonists Astemizole and Terfenadine Compared With Chlorpheniramine and Pyrilamine (Circulation Research, 1995)
- Histamine H1 receptors identified in mammalian brain membranes with [3H]mepyramine. (Proceedings of the National Academy of Sciences of the United States of America, 1978)
- THE BINDING OF [3H]MEPYRAMINE TO HISTAMINE H1 RECEPTORS IN GUINEA-PIG BRAIN (Journal of Neurochemistry, 1978)
- THE DIFFERENTIAL EFFECT OF QUINIDINE AND PYRILAMINE ON THE MYOCARDIAL ACTION POTENTIAL AT VARIOUS RATES OF STIMULATION (Journal of Pharmacology and Experimental Therapeutics, 1957)
- Specific binding of 3H-mepyramine to histamine H1 receptors in intestinal smooth muscle (Nature, 1977)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Pyrilamine
- Mepyramine
- Anthisan
- Mepyramine Maleate
- Pyranisamine
- Boots Bite and Sting Relief
- Kriptin
- Boots Brand of Mepyramine Maleate
-
SMILESCN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O
-
InChIKeyJXYWFNAQESKDNC-UHFFFAOYSA-N
- Pubchem - PYRILAMINE MALEATE
- Wikipedia - pyrilamine maleate
Mepyramine, also known as pyrilamine, is a first generation antihistamine, targeting the H1 receptor. However, it rapidly permeates the brain often causing drowsiness. It also has anticholinergic properties.
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