| Weight | 259.349 g/mol |
|---|---|
| Formula | C16H21NO2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 4 |
Ramelteon (196597-26-9)
Score:
#73 in Neurology
,
#361 in Neuroscience
,
#1644 in Biology
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- Neurochemical properties of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist. (Neuropharmacology, 2005)
- An efficacy, safety, and doseresponse study of Ramelteon in patients with chronic primary insomnia (Sleep Medicine, 2006)
- Effects of ramelteon on patient-reported sleep latency in older adults with chronic insomnia (Sleep Medicine, 2006)
- Ramelteon (TAK-375), a selective MT1/MT2-receptor agonist, reduces latency to persistent sleep in a model of transient insomnia related to a novel sleep environment. (Sleep, 2005)
- Evaluation of the Efficacy and Safety of Ramelteon in Subjects with Chronic Insomnia (Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2007)
- Preventive Effects of Ramelteon on Delirium: A Randomized Placebo-Controlled Trial (JAMA Psychiatry, 2014)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC(=O)NCCC1CCC2=C1C3=C(C=C2)OCC3
-
InChIKeyYLXDSYKOBKBWJQ-UHFFFAOYSA-N
- Pubchem - Ramelteon
- Wikipedia - ramelteon
Ramelteon, marketed as Rozerem among others, is a sleep agent that selectively binds to the MT1 and MT2 receptors in the suprachiasmatic nucleus (SCN), instead of binding to GABAA receptors, such as with drugs like zolpidem. It however does not appear to speed the onset of sleep or the amount of sleep a person gets. It is approved by the U.S.
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