| Weight | 310.335 g/mol |
|---|---|
| Formula | C12H14N4O4S |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
SULFADOXINE (2447-57-6)
Sulforthomidine · Ro 4 4393 · Sulformethoxine
Score:
#342 in Microbiology
,
#2798 in Biology
,
#3505 in Chemistry
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- Molecular Markers for Failure of Sulfadoxine-Pyrimethamine and Chlorproguanil-Dapsone Treatment of Plasmodium falciparum Malaria (The Journal of Infectious Diseases, 2002)
- Efficacy of sulfadoxine-pyrimethamine for prevention of placental malaria in an area of Kenya with a high prevalence of malaria and human immunodeficiency virus infection. (American Journal of Tropical Medicine and Hygiene, 1998)
- Mutations in Plasmodium falciparum Dihydrofolate Reductase and Dihydropteroate Synthase and Epidemiologic Patterns of Pyrimethamine-Sulfadoxine Use and Resistance (The Journal of Infectious Diseases, 1997)
- Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine. (FEBS Journal, 1994)
- Pyrimethaminesulfadoxine resistance in Plasmodium falciparum: what next? (Trends in Parasitology, 2001)
- A COMPARISON OF SULFADOXINE-PYRIMETHAMINE WITH CHLOROQUINE AND PYRIMETHAMINE FOR PREVENTION OF MALARIA IN PREGNANT NIGERIAN WOMEN (American Journal of Tropical Medicine and Hygiene, 2007)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Sulforthomidine
- Ro 4 4393
- Sulformethoxine
- Ro 4-4393
- Sulformetoxine
- Sulphormetoxin
- Sulphorthodimethoxine
- Ro 44393
- Fanasil
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SMILESCOC1=C(N=CN=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N
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- Pubchem - SULFADOXINE
- Wikipedia - sulfadoxine
Sulfadoxine (also spelled sulphadoxine) is an ultra-long-lasting sulfonamide used in combination with pyrimethamine to treat malaria. It was previously used to prevent malaria but due to high levels of resistance, this use is no longer recommended routinely. It is also used, usually in combination with other drugs, to treat or prevent various infections in livestock.
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SULFADOXINE
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