| Weight | 812.018 g/mol |
|---|---|
| Formula | C43H65N5O10 |
| Hydrogen Acceptors | 14 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 11 |
Telithromycin (191114-48-4)
Score:
#168 in Microbiology
,
#1806 in Biology
,
#2152 in Chemistry
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- Sigma-Aldrich - Search for Telithromycin
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- The Effect of Telithromycin in Acute Exacerbations of Asthma (The New England Journal of Medicine, 2006)
- Increasing prevalence of antimicrobial resistance among isolates of Streptococcus pneumoniae from the PROTEKT surveillance study, and compatative in vitro activity of the ketolide, telithromycin (Journal of Antimicrobial Chemotherapy, 2002)
- Diversity of Ribosomal Mutations Conferring Resistance to Macrolides, Clindamycin, Streptogramin, and Telithromycin in Streptococcus pneumoniae (Antimicrobial Agents and Chemotherapy, 2002)
- Structural Insight into the Antibiotic Action of Telithromycin against Resistant Mutants (Journal of Bacteriology, 2003)
- Macrolides and ketolides: azithromycin, clarithromycin, telithromycin (Infectious Disease Clinics of North America, 2004)
- Brief Communication: Severe Hepatotoxicity of Telithromycin: Three Case Reports and Literature Review (Annals of Internal Medicine, 2006)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESCCC1C2(C(C(C(=O)C(CC(C(C(C(=O)C(C(=O)O1)C)C)OC3C(C(CC(O3)C)N(C)C)O)(C)OC)C)C)N(C(=O)O2)CCCCN4C=C(N=C4)C5=CN=CC=C5)C
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- Pubchem - Telithromycin
- Wikipedia - telithromycin
Telithromycin is the first ketolide antibiotic to enter clinical use and is sold under the brand name of Ketek. It is used to treat community acquired pneumonia of mild to moderate severity. After significant safety concerns, the US Food and Drug Administration sharply curtailed the approved uses of the drug in early 2007.
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