Weight | 346.412 g/mol |
---|---|
Formula | C16H18N4O3S |
Hydrogen Acceptors | 6 |
Hydrogen Donors | 1 |
Aromatic Rings | 3 |
Rotatable Bonds | 5 |
Tenatoprazole (113712-98-4, 705969-00-2)
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- Sigma-Aldrich - Tenatoprazole54.50 - 211.00 USD
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- Tenatoprazole, a novel proton pump inhibitor with a prolonged plasma half-life: effects on intragastric pH and comparison with esomeprazole in healthy volunteers. (Alimentary Pharmacology & Therapeutics, 2004)
- Effect on intragastric pH of a PPI with a prolonged plasma half-life: comparison between tenatoprazole and esomeprazole on the duration of acid suppression in healthy male volunteers. (The American Journal of Gastroenterology, 2005)
- Characterization of the inhibitory activity of tenatoprazole on the gastric H+,K+ -ATPase in vitro and in vivo. (Biochemical Pharmacology, 2006)
- A comparative study of the early effects of tenatoprazole 40 mg and esomeprazole 40 mg on intragastric pH in healthy volunteers. (Alimentary Pharmacology & Therapeutics, 2005)
- The pharmacodynamics and pharmacokinetics of S-tenatoprazole-Na 30 mg, 60 mg and 90 mg vs. esomeprazole 40 mg in healthy male subjects. (Alimentary Pharmacology & Therapeutics, 2010)
- Comparison of the effects of fasting morning, fasting evening and fed bedtime administration of tenatoprazole on intragastric pH in healthy volunteers: a randomized three-way crossover study. (Alimentary Pharmacology & Therapeutics, 2006)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=CC(=N3)OC
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InChIKeyZBFDAUIVDSSISP-UHFFFAOYSA-N
- Pubchem - Tenatoprazole
- Wikipedia - tenatoprazole
Tenatoprazole is a proton pump inhibitor drug candidate that was undergoing clinical testing as a potential treatment for reflux oesophagitis and peptic ulcer as far back as 2003. The compound was invented by Mitsubishi Tanabe Pharma and was licensed to Negma Laboratories (part of Wockhardt as of 2007). Mitsubishi reported that tenatoprazole was still in Phase I clinical trials in 2007 and again in 2012.
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