| Weight | 314.86 g/mol |
|---|---|
| Formula | C19H23ClN2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
Triprolidine hydrochloride (6138-79-0, 550-70-9)
Triprolidine · Actidil · Triprolidine, (Z)-Isomer
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- Interaction of triprolidine hydrochloride with serum albumins: thermodynamic and binding characteristics, and influence of site probes. (Journal of Pharmaceutical and Biomedical Analysis, 2011)
- A comparison of triprolidine and clemastine on histamine antagonism and performance tests in man: Implications for the mechanism of drug induced drowsiness (European Journal of Clinical Pharmacology, 1975)
- Acute and subchronic effects of the H1-histamine receptor antagonist ebastine in 10, 20 and 30 mg dose, and triprolidine 10 mg on car driving performance. (British Journal of Clinical Pharmacology, 1993)
- Histamine challenge and anterior nasal rhinometry: their use in the assessment of pseudoephedrine and triprolidine as nasal decongestants in subjects with hayfever. (British Journal of Clinical Pharmacology, 1978)
- Effect of the antihistamines, brompheniramine maleate and triprolidine hydrochloride, on performance in man. (British Journal of Clinical Pharmacology, 1979)
- Effects on the human central nervous system of two isomers of ephedrine and triprolidine, and their interaction. (British Journal of Clinical Pharmacology, 1974)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Triprolidine
- Actidil
- Triprolidine, (Z)-Isomer
- Triprolidine Monohydrochloride, Monohydrate
- Triprolidine Monohydrochloride
- Triprolidine Oxalate, (trans)-Isomer
- Pro Actidil
- Triprolidine Hydrochloride Anhydrous
- Wellcome Brand of Triprolidine
- Triprolidine Monohydrochloride, (Z)-Isomer
- Triprolidine Oxalate
-
SMILESCC1=CC=C(C=C1)C(=CCN2CCCC2)C3=CC=CC=N3.Cl
-
InChIKeyWYUYEJNGHIOFOC-UHFFFAOYSA-N
- Pubchem - Triprolidine hydrochloride
- Wikipedia - triprolidine hydrochloride
Triprolidine is an over-the-counter antihistamine with anticholinergic properties. It is used to combat the symptoms associated with allergies and is sometimes combined with other cold medications designed to provide general relief for flu-like symptoms. Like many antihistamines, the most common side effect is drowsiness.
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Synthesis
Reactant
+
4-Chlorotoluene
(Stille)
Reactant
+
PYRROLIDINE
(Chan-Lam coupling reaction)
4-Tolylboronic acid
+
Reactant
(Suzuki)
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Triprolidine hydrochloride
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