Weight | 100.117 g/mol |
---|---|
Formula | C5H8O2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 0 |
Aromatic Rings | 0 |
Rotatable Bonds | 0 |
Tetrahydro-4H-pyran-4-one (29943-42-8)
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- The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents (Neuropharmacology, 2011)
- Design and Discovery of 6-[(3S,4S)-4-Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (PF-04447943), a Selective Brain Penetrant PDE9A Inhibitor for the Treatment of Cognitive Disorders (Journal of Medicinal Chemistry, 2012)
- Improved Procedures for the Preparation of Tetrahydro-4H-pyran-4-one and 5,6-Dihydro-4-methoxy-2H-pyran. (Synthesis, 1975)
- A convenient preparation of tetrahydro-4H-pyran-4-one (Journal of The Chemical Society C: Organic, 1970)
- Synthesis and conformational studies of tertiary alcohols derived from tetrahydro-4H-pyran-4-one and tetrahydrothiopyran-4-one (Phosphorus Sulfur and Silicon and The Related Elements, 2005)
- Access to 3,5,6,7-tetrahydro-2H-[1]benzopyran ring system from 2,3,5,6,7,8-hexahydrobenzo-4H-pyran-4-one derivatives (Journal of Organic Chemistry, 1984)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1COCCC1=O
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InChIKeyJMJRYTGVHCAYCT-UHFFFAOYSA-N
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