| Weight | 189.224 g/mol |
|---|---|
| Formula | C6H12N3PS |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 3 |
thiotepa (52-24-4)
Triethylenethiophosphoramide · Tespa · Thio Tepa
Score:
#352 in Biochemistry
,
#1269 in Biology
,
#1468 in Chemistry
"What do you need help with?"
LabBot
- Sigma-Aldrich - Search for thiotepa
- Fisher Scientific - Search for thiotepa
- TCI - Search for thiotepa
- A phase II study of high-dose cyclophosphamide, thiotepa, and carboplatin with autologous marrow support in women with measurable advanced breast cancer responding to standard-dose therapy (Journal of Clinical Oncology, 1992)
- Randomized prospective comparison of intraventricular methotrexate and thiotepa in patients with previously untreated neoplastic meningitis. Eastern Cooperative Oncology Group. (Journal of Clinical Oncology, 1993)
- High-dose carboplatin, thiotepa, and etoposide with autologous stem-cell rescue for patients with recurrent medulloblastoma. Children's Cancer Group. (Journal of Clinical Oncology, 1998)
- Pilot study of high-dose thiotepa and etoposide with autologous bone marrow rescue in children and young adults with recurrent CNS tumors. The Children's Cancer Group. (Journal of Clinical Oncology, 1996)
- Thiotepa in the treatment of tumours of the bladder. (The Lancet, 1961)
- COMPARISONS OF PLACEBO, PYRIDOXINE, AND TOPICAL THIOTEPA IN PREVENTING RECURRENCE OF STAGE I BLADDER CANCER* (Urology, 1977)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H300: Fatal if swallowed
Danger Acute toxicity, oral - Category 1, 2 - H350: May cause cancer
Danger Carcinogenicity - Category 1A, 1B - H371: May cause damage to organs
Warning Specific target organ toxicity, single exposure - Category 2 - Triethylenethiophosphoramide
- Tespa
- Thio Tepa
- AI3-24916
- AI3 24916
- NSC6396
- Tespamin
- Tris(1-aziridinyl)phosphine Sulfide
- Thiophosphamide
- Thio-Tepa
- AI324916
- NSC 6396
- NSC-6396
- Girostan
-
SMILESC1CN1P(=S)(N2CC2)N3CC3
-
InChIKeyFOCVUCIESVLUNU-UHFFFAOYSA-N
- Pubchem - thiotepa
- Wikipedia - thiotepa
Thiotepa (INN, chemical name: N,N,N-triethylenethiophosphoramide) is an alkylating agent used to treat cancer. Thiotepa is an organophosphorus compound with the formula SP(NC2H4)3. It is a analog of N,N,N-triethylenephosphoramide (TEPA), which contains tetrahedral phosphorus and is structurally akin to phosphate.
Suppliers
Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
External Links
Similar Compounds
Hexabutylthiophosphoramide
(3949-47-1)
15 alternate names
3 suppliers
Tris(diethylamino)phosphine
(2283-11-6)
15 alternate names
3 suppliers
Tris(dibutylamino)phosphine
(5848-65-7)
15 alternate names
3 suppliers
94317-64-3
(94317-64-3)
15 alternate names
3 suppliers
Hexamethylphosphorous triamide
(1608-26-0)
15 alternate names
3 suppliers
Dipin
(738-99-8)
15 alternate names
3 suppliers
6415-07-2
(6415-07-2)
15 alternate names
3 suppliers
51219-90-0
(51219-90-0)
15 alternate names
3 suppliers
Trimorpholinophosphine oxide
(4441-12-7)
15 alternate names
3 suppliers
Bis(diethylamino)phosphoryl chloride
(1794-24-7)
15 alternate names
3 suppliers
102691-36-1
(102691-36-1)
15 alternate names
3 suppliers
MIPAFOX
(371-86-8)
15 alternate names
1 safety hazard
3 suppliers
Cyclophosphamide monohydrate
(6055-19-2)
15 alternate names
4 safety hazards
3 suppliers
68641-49-6
(68641-49-6)
15 alternate names
3 suppliers
2-amino-1,3,8-triazaspiro[4.5]dec-1-en-4-one dihydrochloride
(1269106-47-9)
15 alternate names
3 suppliers
2-(dimethylamino)-1,3,8-triazaspiro[4.5]dec-1-en-4-one dihydrochloride hydrate
(1227465-49-7)
15 alternate names
3 suppliers
56602-33-6
(56602-33-6)
15 alternate names
3 suppliers
p-Bromo-dcba
(2743-05-7)
15 alternate names
3 suppliers
2-(thiophen-2-yl)ethanimidamide hydrochloride
(6449-64-5)
15 alternate names
3 suppliers
2-Benzylaziridine
(13906-90-6)
15 alternate names
3 suppliers
2-(2-AMINO-1,3-THIAZOL-5-YL)-N-METHYLACETAMIDE
(1172707-63-9)
15 alternate names
3 suppliers
N-(4-Bromobenzyl)-N-isopropylpropan-2-amine
(98816-61-6)
15 alternate names
3 suppliers
81477-94-3
(81477-94-3)
15 alternate names
3 suppliers
(4R)-4-(dimethylamino)-L-proline
(1256636-28-8)
15 alternate names
3 suppliers
m-Bromo-dcba
(2361-59-3)
15 alternate names
3 suppliers
N-benzylaspartic acid
(5555-22-6)
15 alternate names
3 suppliers
1-(2-phenylethyl)proline
(56014-49-4)
15 alternate names
3 suppliers
1-benzylazetidine-2-carboxylic acid
(18085-40-0)
15 alternate names
3 suppliers
2-methyl-1,3,8-triazaspiro[4.5]dec-1-en-4-one dihydrochloride
(1269054-82-1)
15 alternate names
3 suppliers
62374-67-8
(62374-67-8)
15 alternate names
3 suppliers
(4S)-4-amino-1-methyl-L-proline
(1308319-48-3)
15 alternate names
3 suppliers
4-(2-amino-2-oxoethoxy)benzenesulfonyl chloride
(69986-21-6)
15 alternate names
3 suppliers
Benzenemethanamine, 2,5-dichloro-N-ethyl-
(90390-17-3)
15 alternate names
3 suppliers
1-(4-bromobenzyl)pyrrolidine hydrochloride
(1609402-88-1)
15 alternate names
3 suppliers
N-(4-bromobenzyl)-2-propen-1-amine
(99359-28-1)
15 alternate names
3 suppliers
4-[2-(acetylamino)ethyl]benzenesulfonyl chloride
(35450-53-4)
15 alternate names
3 suppliers
69555-14-2
(69555-14-2)
15 alternate names
3 suppliers
13632-07-0
(13632-07-0)
15 alternate names
3 suppliers
methyl (4R)-4-(dimethylamino)-L-prolinate dihydrochloride
(1609388-38-6)
15 alternate names
3 suppliers
methyl (4R)-4-(dimethylamino)-L-prolinate
(1163706-98-6, 1163857-73-5)
15 alternate names
3 suppliers
(4-BROMOBENZYL)PROPYLAMINE
(150869-52-6)
15 alternate names
3 suppliers
(4-bromobenzyl)isopropylamine
(60376-97-8)
15 alternate names
3 suppliers
N-(4-bromobenzyl)ethanamine hydrochloride
(1129306-09-7)
15 alternate names
3 suppliers
81167-39-7
(81167-39-7)
15 alternate names
3 suppliers
N-Benzyl-2-chloro-N-isopropyl-acetamide
(39086-63-0)
15 alternate names
3 suppliers
ethyl 2-amino-4-ethyl-5-methylthiophene-3-carboxylate
(82546-91-6)
15 alternate names
3 suppliers
N-benzyl-3-(4-methoxyphenoxy)propan-1-amine
(433947-02-5)
15 alternate names
3 suppliers
Uramil
(118-78-5)
15 alternate names
3 suppliers
2-(5,6,7,8-tetrahydro-2-naphthalenyloxy)butanoic acid
(869947-98-8)
15 alternate names
3 suppliers
2-amino-4,5-dimethylthiophene-3-carboxylic acid
(55502-96-0)
15 alternate names
3 suppliers
(8-methoxy-3,4-dihydro-2H-chromen-3-yl)amine
(112904-73-1)
15 alternate names
3 suppliers
N-Methyl-DL-aspartic acid
(17833-53-3)
15 alternate names
3 suppliers
N-Methyl-L-aspartic acid
(4226-18-0)
15 alternate names
3 suppliers
Glutathione reduced ethyl ester
(92614-59-0, 118421-50-4)
15 alternate names
3 suppliers
43189-50-0
(7511-46-8)
15 alternate names
3 suppliers
methyl 2-amino-4-ethyl-5-methylthiophene-3-carboxylate
(4815-25-2)
15 alternate names
3 suppliers
AC1LEPGY
(17027-50-8, 5624-26-0)
15 alternate names
3 suppliers
n-benzyl-n-ethylpiperidin-4-amine
(76167-64-1)
15 alternate names
3 suppliers
3-amino-2-(3-thienylmethyl)-1-propanol
(929974-90-3)
15 alternate names
3 suppliers
methyl (4S)-4-amino-1-methyl-L-prolinate dihydrochloride
(1609388-59-1, 1300698-39-8)
15 alternate names
3 suppliers
(isopropylamino)(oxo)acetic acid
(29262-57-5)
15 alternate names
3 suppliers
1-(2-Chlorobenzyl)piperidin-4-amine dihydrochloride
(57645-60-0)
15 alternate names
3 suppliers
1-(2-chlorobenzyl)piperidin-4-amine
(92539-15-6)
15 alternate names
3 suppliers
4-Amino-1-benzylpiperidine-4-carboxylic Acid
(39143-25-4)
15 alternate names
3 suppliers
1-ethylpyrrolidine-2-carboxylic acid
(98435-76-8, 165552-33-0)
15 alternate names
3 suppliers
1-Benzyl-4-(dimethylamino)piperidine
(64168-08-7)
15 alternate names
3 suppliers
2-(dimethylamino)butanoic acid
(170941-86-3)
15 alternate names
3 suppliers
1-ethyl-D-proline hydrochloride
(1777812-89-1)
15 alternate names
3 suppliers
(tert-butylamino)(oxo)acetic acid
(169772-25-2)
15 alternate names
3 suppliers
ethyl 2-(3,4-dimethylanilino)-2-oxoacetate
(24451-17-0)
15 alternate names
3 suppliers
N-(4-bromobenzyl)-2-butanamine hydrochloride
(1158472-86-6)
15 alternate names
3 suppliers
[2-(3-propoxyphenyl)ethyl]amine hydrochloride
(103686-13-1)
15 alternate names
3 suppliers
Ethyl 2-amino-4-methylthiophene-3-carboxylate
(43088-42-2)
15 alternate names
3 suppliers
N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine
(55-51-6)
15 alternate names
3 suppliers
1-(3-propoxyphenyl)ethanamine
(925650-26-6)
15 alternate names
3 suppliers
AC1LTC02
(1931958-05-2)
15 alternate names
3 suppliers
8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione
(39124-19-1)
15 alternate names
3 suppliers
1-(piperidin-4-yl)pyrrolidine-2-carboxylic acid
15 alternate names
3 suppliers
1-(thiophen-2-ylmethyl)piperidin-4-amine dihydrochloride
(57645-59-7)
15 alternate names
3 suppliers
1-(4-piperidinyl)-L-proline dihydrochloride
(1609388-60-4)
15 alternate names
3 suppliers
33996-30-4
(33996-30-4)
15 alternate names
3 suppliers
(2R)-1-propanoylpyrrolidine-2-carboxylic acid
(59785-64-7, 1344945-82-9, 59785-66-9)
15 alternate names
3 suppliers
3-PHENOXYPYRROLIDINE HYDROCHLORIDE
(21767-15-7)
15 alternate names
3 suppliers
N-(2-Amino-4,5-dimethylphenyl)acetamide
(117044-02-7)
15 alternate names
3 suppliers
2-amino-5-methylthiophene-3-carboxylic acid
(41940-47-0)
15 alternate names
3 suppliers
20348-21-4
(20348-21-4)
15 alternate names
3 suppliers
N-(4-bromobenzyl)-2-methyl-1-propanamine hydrochloride
(1158624-48-6)
15 alternate names
3 suppliers
N-(4-bromobenzyl)-2-methyl-2-propanamine hydrochloride
(1209906-44-4)
15 alternate names
3 suppliers
Phenethyl isocyanate
(1943-82-4)
15 alternate names
4 safety hazards
3 suppliers
3-(4,5-dihydro-1H-imidazol-2-yl)pyridine
(6302-53-0)
15 alternate names
3 suppliers
[3-(3-ethylphenoxy)propyl]methylamine hydrochloride
(1609402-79-0)
15 alternate names
3 suppliers
2-Methyl-2-phenylaziridine
(22596-57-2)
15 alternate names
3 suppliers
1-(4-bromobenzyl)piperidine hydrochloride
(1051368-74-1)
15 alternate names
3 suppliers
AN-465/42518790
(893581-95-8)
15 alternate names
3 suppliers
thiotepa
CAS Directory
