| Weight | 260.271 g/mol |
|---|---|
| Formula | C9H12N2O5S |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
TIAZOFURIN (60084-10-8)
Score:
#1789 in Biochemistry
,
#3911 in Biology
,
#4924 in Chemistry
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- Biochemically Directed Therapy of Leukemia with Tiazofurin, a Selective Blocker of Inosine 5-Phosphate Dehydrogenase Activity (Cancer Research, 1989)
- Modulation of IMP dehydrogenase activity and guanylate metabolism by tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide). (Journal of Biological Chemistry, 1984)
- Synergistic antiviral effects of ribavirin and the C-nucleoside analogs tiazofurin and selenazofurin against togaviruses, bunyaviruses, and arenaviruses. (Antimicrobial Agents and Chemotherapy, 1984)
- Biochemical differences among four inosinate dehydrogenase inhibitors, mycophenolic acid, ribavirin, tiazofurin, and selenazofurin, studied in mouse lymphoma cell culture. (Cancer Research, 1985)
- Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogues. Synthesis, Structure, Antitumor Activity, and Interactions with Inosine Monophosphate Dehydrogenase (Journal of Medicinal Chemistry, 1995)
- Ribavirin, tiazofurin, and selenazofurin: mononucleotides and nicotinamide adenine dinucleotide analogues. Synthesis, structure, and interactions with IMP dehydrogenase (Journal of Medicinal Chemistry, 1985)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=C(N=C(S1)C2C(C(C(O2)CO)O)O)C(=O)N
-
InChIKeyFVRDYQYEVDDKCR-UHFFFAOYSA-N
- Pubchem - TIAZOFURIN
- Wikipedia - tiazofurin
Tiazofurin is an inhibitor of IMP dehydrogenase. Tiazofurin and its analogues are under investigation for potential use in the treatment of cancer.
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